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Previous Volume 328:1616-1620 June 3, 1993 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the United States the average daily intake of dietary iron ranges from 10 to 30 mg, but only about 1 mg is absorbed, to balance precisely the loss due to the sloughing of intact cells containing iron. Iron absorption can be increased if iron stores are depleted (usually through blood loss), and in genetically normal people absorption decreases with iron overload^1,2 (usually from multiple transfusions). Iron balance is regulated at the absorptive step, but the mechanism by which the intestinal mucosa accomplishes this has not been defined. The defect responsible for hereditary hemochromatosis is malregulation of intestinal iron absorption^3,4. . . [Full Text of this Article]

Frequency and Genetic Transmission

Screening Strategy

Treatment

Source Information

From the Departments of Medicine, University of Utah College of Medicine and LDS Hospital, both in Salt Lake City.

Address reprint requests to Dr. Kushner at 4C-334, Dept. of Medicine, University of Utah College of Medicine, 50 N. Medical Dr., Salt Lake City, UT 84132.

References

Related Letters:

Screening for Hemochromatosis
Billings P. R., Barash C., Geller L. N., Alper J. S., Maguire G. A., Edwards C. Q., Kushner J. P.
Extract | Full Text  
N Engl J Med 1993; 329:2037-2038, Dec 30, 1993. Correspondence

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