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Previous Volume 328:1706-1708 June 10, 1993 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Coronary angiograms are found to be normal in approximately 10 to 20 percent of patients undergoing cardiac catheterization to evaluate angina-like chest pain. Although their prognosis is good,¹ most of these patients continue to experience chest pain despite reassurance that they do not have obstructive coronary disease; the pain results in continued hospitalizations, more cardiac catheterizations, and diminished quality of life and ability to work². The mechanisms of pain in these patients, even those with ischemic-appearing electrocardiographic responses to exercise (sometimes referred to as syndrome X), continue to be controversial, as evidenced by numerous studies with often conflicting results, . . . [Full Text of this Article]

References

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• Schindler, T H, Nitzsche, E, Magosaki, N, Brink, I, Mix, M, Olschewski, M, Solzbach, U, Just, H (2003). Regional myocardial perfusion defects during exercise, as assessed by three dimensional integration of morphology and function, in relation to abnormal endothelium dependent vasoreactivity of the coronary microcirculation. Heart 89: 517-526 [Abstract] [Full Text]  
• Spalding, L., Reay, E., Kelly, C. (2003). Cause and outcome of atypical chest pain in patients admitted to hospital. JRSM 96: 122-125 [Abstract] [Full Text]  
• Zeiher, A. M., Krause, T., Schachinger, V., Minners, J., Moser, E. (1995). Impaired Endothelium-Dependent Vasodilation of Coronary Resistance Vessels Is Associated With Exercise-Induced Myocardial Ischemia. Circulation 91: 2345-2352 [Abstract] [Full Text]  
• Rossen, J. D., Agmon, Y., Gorlin, R., Abbott, E.C., Egashira, K., Takeshita, A. (1993). Endothelial Dysfunction in Microvascular Angina. NEJM 329: 1739-1740 [Full Text]