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This is a misconception. My prospective studies3,4,5 of erythroplastic lesions have focused primarily on early invasive carcinoma. Supporting Shedd's6 original clinical observation, these studies have demonstrated that erythroplasia is the earliest clinical sign of asymptomatic squamous carcinoma, not precancer. I did not report on the transformation from precancer to cancer. The initial biopsies of the erythroplastic lesions that persisted for
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