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Correspondence
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Volume 328:1847-1850 June 24, 1993 Number 25
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CD4+ T-Lymphocytopenia without HIV Infection

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 by Smith, D. K.
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To the Editor: Reports in the February 11 issue of the Journal review the epidemiology of "AIDS" without human immunodeficiency virus (HIV) infection, or idiopathic CD4+ T-lymphocytopenia1,2,3,4,5,6,7. Two of these studies report that AIDS is absent and persistent idiopathic CD4+ T-lymphocytopenia is rare in large, prospective studies of seronegative transfusion recipients5 and homosexual men6. Similarly, we have not found persistent idiopathic CD4+ T-lymphocytopenia or AIDS-defining conditions in a seven-year prospective study of 732 men seronegative for HIV type 1. Our study subjects are part of the San Francisco Men's Health Study and San Francisco General Hospital Cohort, and . . . [Full Text of this Article]

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