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Correspondence
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Volume 328:1853-1854 June 24, 1993 Number 25
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Central Venous Pressure in Space

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To the Editor: When a person enters zero gravity, a large amount of fluid (1 to 2 liters) shifts toward the head. The response to this shift includes the principal cardiovascular effects of spaceflight -- e.g., hypovolemia, dehydration, and postflight orthostatic intolerance1. On earth, a similar headward shift of fluid increases central venous pressure2; in space, however, peripheral antecubital venous pressure does not increase3,4. It is not known whether such peripheral measurements reflect central venous pressure. Only direct, continuous measurements recorded during a change from earth's gravity (1 g) to zero gravity can resolve these controversies. In . . . [Full Text of this Article]

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More on Central Venous Pressure in Space
Coleman L. B., Buckey J. C.
Extract | Full Text  
N Engl J Med 1993; 329:1822, Dec 9, 1993. Correspondence

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