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Previous Volume 328:1857-1858 June 24, 1993 Number 25 Next

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By Alan H. Lockwood. 151 pp., illustrated. Boston, Butterworth-Heinemann, 1992. $44.95. ISBN 0-7506-9324-0.

The last overview of hepatic encephalopathy, a clinical problem in which two distinct disciplines meet, was written by a hepatologist more than a decade ago; it was criticized for its omissions of neurochemical issues. Now Lockwood, a neurologist as well as specialist in nuclear medicine, has written a short monograph covering recent advances in the field. It has succeeded in some aspects while falling short in others.

Controversy has characterized research in hepatic encephalopathy. Of the nine chapters of this book, five deal with different candidate neurotoxins that have been studied over the past four decades. The role of ammonia, . . . [Full Text of this Article]

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