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Volume 328:153-158 January 21, 1993 Number 3 Next

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ABSTRACT

Background The aim of this study was to investigate the causes, severity, and prevalence of dementia in a representative sample of 494 85-year-olds living in Gothenburg, Sweden.

Methods The study included a psychiatric interview, neuropsychological and physical examinations, comprehensive laboratory tests, electrocardiography, chest radiography, computed tomography (CT) of the head, and analysis of cerebrospinal fluid. A person close to each subject was also interviewed. Dementia was defined according to the criteria proposed in the Diagnostic and Statistical Manual of Mental Disorders (third edition, revised), Alzheimer's disease according to the criteria of the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association, and vascular dementia according to recently proposed criteria that incorporate information from CT scanning and the patient's neurologic history.

Results The prevalence of dementia was 29.8 percent (147 subjects). The condition was mild in 8.3 percent, moderate in 10.3 percent, and severe in 11.1 percent. There were no significant sex-related differences in prevalence or severity. Of the subjects with dementia, 43.5 percent had Alzheimer's disease, 46.9 percent had vascular dementia (multi-infarct dementia in 34.6 percent, dementia related to cerebral hypoperfusion in 4.1 percent, and mixed dementia in 8.2 percent), and 9.5 percent had dementia due to other causes. The three-year mortality rate was 23.1 percent in the subjects without dementia, 42.2 percent in the patients with Alzheimer's disease, and 66.7 percent in the patients with vascular dementia. Infarcts detected by CT scanning were significantly more common in the subjects with dementia than in those without it (27.9 percent vs. 12.6 percent).

Conclusions Dementia was present in nearly a third of unselected 85-year-olds in Sweden. Almost half these subjects appeared to have vascular dementia, which may currently be more amenable to prevention or treatment than Alzheimer's disease.

Source Information

From the Department of Psychiatry, Sahlgrenska Hospital (I.S., L.N.), and the Department of Radiology, Ostra sjukhuset (B.P., L.-A.A.), both in Gothenburg, Sweden; and the Section of Geriatric Medicine, Department of Medicine, University of Illinois, Chicago (A.S.).

Address reprint requests to Dr. Skoog at the Department of Psychiatry, Sahlgrenska Hospital, S-413 45 Gothenburg, Sweden.

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• Andersen-Ranberg, K., Vasegaard, L., Jeune, B. (2001). Dementia Is Not Inevitable: A Population-Based Study of Danish Centenarians. J. Gerontol. B Psychol. Sci. Soc. Sci. 56: P152-P159 [Abstract] [Full Text]  
• Bekkelund, S. I., Kujala, I., Rosenvinge, B. (2001). Unrecognized Dementia in Elderly Patients Admitted to Hospital with Psychiatric Symptoms. J Geriatr Psychiatry Neurol 14: 7-10 [Abstract]  
• Hebert, L. E., Scherr, P. A., McCann, J. J., Beckett, L. A., Evans, D. A. (2001). Is the Risk of Developing Alzheimer's Disease Greater for Women than for Men?. Am J Epidemiol 153: 132-136 [Abstract] [Full Text]  
• LIDDELL, M. B., LOVESTONE, S., OWEN, M. J. (2001). Genetic risk of Alzheimer's disease: advising relatives. Br. J. Psychiatry 178: 7-11 [Abstract] [Full Text]  
• Pohjasvaara, T., Mantyla, R., Ylikoski, R., Kaste, M., Erkinjuntti, T. (2000). Comparison of Different Clinical Criteria (DSM-III, ADDTC, ICD-10, NINDS-AIREN, DSM-IV) for the Diagnosis of Vascular Dementia. Stroke 31: 2952-2957 [Abstract] [Full Text]  
• Lee, J.-H., Olichney, J. M., Hansen, L. A., Hofstetter, C. R., Thal, L. J. (2000). Small Concomitant Vascular Lesions Do Not Influence Rates of Cognitive Decline in Patients With Alzheimer Disease. Arch Neurol 57: 1474-1479 [Abstract] [Full Text]  
• Pohjasvaara, T., Mantyla, R., Salonen, O., Aronen, H. J., Ylikoski, R., Hietanen, M., Kaste, M., Erkinjuntti, T. (2000). How Complex Interactions of Ischemic Brain Infarcts, White Matter Lesions, and Atrophy Relate to Poststroke Dementia. Arch Neurol 57: 1295-1300 [Abstract] [Full Text]  
• Hy, L. X., Keller, D. M. (2000). Prevalence of AD among whites: A summary by levels of severity. Neurology 55: 198-204 [Abstract] [Full Text]  
• Shua-Haim, J. R., Shua-Haim, V., Comsti, E., Ross, J. S. (2000). Donepezil (Aricept(R)) treatment of multi infarct dementia: The caregivers and clinical impression. AM J ALZHEIMERS DIS OTHER DEMEN 15: 201-211 [Abstract]  
• Barba, R., Martinez-Espinosa, S., Rodriguez-Garcia, E., Pondal, M., Vivancos, J., Del Ser, T. (2000). Poststroke Dementia : Clinical Features and Risk Factors. Stroke 31: 1494-1501 [Abstract] [Full Text]  
• Chui, H. C., Mack, W., Jackson, J. E., Mungas, D., Reed, B. R., Tinklenberg, J., Chang, F.-L., Skinner, K., Tasaki, C., Jagust, W. J. (2000). Clinical Criteria for the Diagnosis of Vascular Dementia: A Multicenter Study of Comparability and Interrater Reliability. Arch Neurol 57: 191-196 [Abstract] [Full Text]  
• Pohjasvaara, T, Mantyla, R, Aronen, H J, Leskela, M, Salonen, O, Kaste, M, Erkinjuntti, T (1999). Clinical and radiological determinants of prestroke cognitive decline in a stroke cohort. J. Neurol. Neurosurg. Psychiatry 67: 742-748 [Abstract] [Full Text]  
• Del Ser, T., Hachinski, V., Merskey, H., Munoz, D. G. (1999). An autopsy-verified study of the effect of education on degenerative dementia. Brain 122: 2309-2319 [Abstract] [Full Text]  
• Verghese, J., Crystal, H. A., Dickson, D. W., Lipton, R. B. (1999). Validity of clinical criteria for the diagnosis of dementia with Lewy bodies. Neurology 53: 1974-1974 [Abstract] [Full Text]  
• Massoud, F., Devi, G., Stern, Y., Lawton, A., Goldman, J. E., Liu, Y., Chin, S. S., Mayeux, R. (1999). A Clinicopathological Comparison of Community-Based and Clinic-Based Cohorts of Patients With Dementia. Arch Neurol 56: 1368-1373 [Abstract] [Full Text]  
• Gallo, J. J., Lebowitz, B. D. (1999). The Epidemiology of Common Late-Life Mental Disorders in the Community: Themes for the New Century. Psychiatr. Serv. 50: 1158-1166 [Abstract] [Full Text]  
• Guo, Z., Fratiglioni, L., Zhu, L., Fastbom, J., Winblad, B., Viitanen, M. (1999). Occurrence and Progression of Dementia in a Community Population Aged 75 Years and Older: Relationship of Antihypertensive Medication Use. Arch Neurol 56: 991-996 [Abstract] [Full Text]  
• von Strauss, E., Viitanen, M., De Ronchi, D., Winblad, B., Fratiglioni, L. (1999). Aging and the Occurrence of Dementia: Findings From a Population-Based Cohort With a Large Sample of Nonagenarians. Arch Neurol 56: 587-592 [Abstract] [Full Text]  
• Richards, S. S., Hendrie, H. C. (1999). Diagnosis, Management, and Treatment of Alzheimer Disease: A Guide for the Internist. Arch Intern Med 159: 789-798 [Abstract] [Full Text]  
• Bousser, M.-G. (1999). Stroke in Women : The 1997 Paul Dudley White International Lecture. Circulation 99: 463-467 [Full Text]  
• Zhu, L., Fratiglioni, L., Guo, Z., Aguero-Torres, H., Winblad, B., Viitanen, M. (1998). Association of Stroke With Dementia, Cognitive Impairment, and Functional Disability in the Very Old : A Population-Based Study. Stroke 29: 2094-2099 [Abstract] [Full Text]  
• O'Connell, J. E, Gray, C. S, French, J. M, Robertson, I. H (1998). Atrial fibrillation and cognitive function: case-control study. J. Neurol. Neurosurg. Psychiatry 65: 386-389 [Abstract] [Full Text]  
• Gao, S., Hendrie, H. C., Hall, K. S., Hui, S. (1998). The Relationships Between Age, Sex, and the Incidence of Dementia and Alzheimer Disease: A Meta-analysis. Arch Gen Psychiatry 55: 809-815 [Abstract] [Full Text]  
• Aevarsson, O., Svanborg, A., Skoog, I. (1998). Seven-Year Survival Rate After Age 85 Years: Relation to Alzheimer Disease and Vascular Dementia. Arch Neurol 55: 1226-1232 [Abstract] [Full Text]  
• Kilander, L., Andren, B., Nyman, H., Lind, L., Boberg, M., Lithell, H. (1998). Atrial Fibrillation Is an Independent Determinant of Low Cognitive Function : A Cross-Sectional Study in Elderly Men. Stroke 29: 1816-1820 [Abstract] [Full Text]  
• Skoog, I., Andreasson, L.-A., Landahl, S., Lernfelt, B. (1998). A Population-Based Study on Blood Pressure and Brain Atrophy in 85-Year-Olds. Hypertension 32: 404-409 [Abstract] [Full Text]  
• Bowler, J. V, Munoz, D. G, Merskey, H., Hachinski, V. (1998). Factors affecting the age of onset and rate of progression of Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 65: 184-190 [Abstract] [Full Text]  
• Hendrie, H. C. (1998). Epidemiology of Dementia and Alzheimer's Disease. AJGP 6: 3S-18 [Abstract] [Full Text]  
• Kase, C. S., Wolf, P. A., Kelly-Hayes, M., Kannel, W. B., Beiser, A., D'Agostino, R. B. (1998). Intellectual Decline After Stroke : The Framingham Study. Stroke 29: 805-812 [Abstract] [Full Text]  
• Kilander, L., Nyman, H., Boberg, M., Hansson, L., Lithell, H. (1998). Hypertension Is Related to Cognitive Impairment : A 20-Year Follow-up of 999 Men. Hypertension 31: 780-786 [Abstract] [Full Text]  
• Skoog, I., Hesse, C., Aevarsson, O., Landahl, S., Wahlström, J., Fredman, P., Blennow, K. (1998). A population study of apoE genotype at the age of 85: relation to dementia, cerebrovascular disease, and mortality. J. Neurol. Neurosurg. Psychiatry 64: 37-43 [Abstract] [Full Text]  
• Pohjasvaara, T., Erkinjuntti, T., Ylikoski, R., Hietanen, M., Vataja, R., Kaste, M. (1998). Clinical Determinants of Poststroke Dementia. Stroke 29: 75-81 [Abstract] [Full Text]  
• Erkinjuntti, T., Ostbye, T., Steenhuis, R., Hachinski, V. (1997). The Effect of Different Diagnostic Criteria on the Prevalence of Dementia. NEJM 337: 1667-1674 [Abstract] [Full Text]  
• Ferrucci, L., Guralnik, J. M., Pahor, M., Harris, T., Corti, M.-C., MHS, M.-C., Hyman, B. T., Wallace, R. B., Havlik, R. J. (1997). Apolipoprotein E {epsilon}2 Allele and Risk of Stroke in the Older Population. Stroke 28: 2410-2416 [Abstract] [Full Text]  
• Pohjasvaara, T., Erkinjuntti, T., Vataja, R., Kaste, M. (1997). Dementia Three Months After Stroke : Baseline Frequency and Effect of Different Definitions of Dementia in the Helsinki Stroke Aging Memory Study (SAM) Cohort. Stroke 28: 785-792 [Abstract] [Full Text]  
• Lindsay, J., Hebert, R., Rockwood, K. (1997). The Canadian Study of Health and Aging : Risk Factors for Vascular Dementia. Stroke 28: 526-530 [Abstract] [Full Text]  
• Gorelick, P. B. (1997). Status of Risk Factors for Dementia Associated With Stroke. Stroke 28: 459-463 [Abstract] [Full Text]  
• Roman, G. C. (1996). From UBOs to Binswanger's Disease: Impact of Magnetic Resonance Imaging on Vascular Dementia Research. Stroke 27: 1269-1273 [Full Text]  
• Skoog, I. (1996). Sex and Swedish 85-Year-Olds. NEJM 334: 1140-1141 [Full Text]  
• Amar, K., Wilcock, G. (1996). Fortnightly Review: Vascular dementia. BMJ 312: 227-231 [Abstract] [Full Text]  
• Zarit, S. H., Johansson, B., Malmberg, B. (1995). Changes in Functional Competency in the Oldest Old: A Longitudinal Study. J Aging Health 7: 3-23 [Abstract]  
• Campion, E. W. (1994). The Oldest Old. NEJM 330: 1819-1820 [Full Text]  
• Plomin, R, Owen, M., McGuffin, P (1994). The genetic basis of complex human behaviors. Science 264: 1733-1739 [Abstract]  
• Owen, M, Liddell, M, McGuffin, P (1994). Alzheimer's disease. BMJ 308: 672-673 [Full Text]  
• Roman, G. C., Goldstein, M., Monfort, J.-C., Skoog, I., Nilsson, L., Svanborg, A. (1993). A Population-Based Study of Dementia in 85-Year-Olds. NEJM 329: 63-64 [Full Text]  
• (1993). VASCULAR DEMENTIA IS COMMON IN THE VERY ELDERLY. JWatch General 1993: 5-5 [Full Text]  
• Larson, E. B. (1993). Illnesses Causing Dementia in the Very Elderly. NEJM 328: 203-205 [Full Text]