Head and Neck Cancer

doi:10.1056/NEJM199301213280306

Volume 328:184-194		January 21, 1993		Number 3

Head and Neck Cancer

Everett E. Vokes, Ralph R. Weichselbaum, Scott M. Lippman, and Waun Ki Hong

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Head and neck cancer was last reviewed in the Journal in 1983¹.At that time, there was promising new information on a possiblerole for chemotherapy¹^,². During the past decade, chemotherapyhas undergone further investigation and important clinical advanceshave been made in chemoprevention, organ preservation, and thesimultaneous use of chemotherapy and radiation. In this review,we shall discuss the diagnosis of and standard therapy for headand neck cancer, as well as the status of recent basic and clinicalinvestigations.

Epidemiology

Head and neck cancer, as defined here, includes the common squamous-cellcarcinomas of the oral cavity, . . . [Full Text of this Article]

Biology

Diagnosis and Staging

Lymph-Node Metastases

Other Medical Problems in Patients with Head and Neck Cancer

Natural History and Standard Therapy

Nasopharynx

Oral Cavity

Oropharynx

Hypopharynx

Larynx

Management of Cervical Lymph Nodes

Clinical Investigations

Chemotherapy for Metastatic or Recurrent Disease

Combined Therapy for Local or Regionally Advanced Disease

Induction and Adjuvant Chemotherapy

Organ Preservation

Concomitant Chemotherapy and Radiation Therapy and Altered Fractionation Radiation Therapy

Chemoprevention

Outlook

Source Information

From the Department of Medicine, Section of Hematology/Oncology (E.E.V.), and the Department of Radiation and Cellular Oncology (E.E.V., R.R.W.), University of Chicago, Chicago, and the Department of Thoracic/ Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston (S.M.L., W.K.H.).

Address reprint requests to Dr. Vokes at the University of Chicago Medical Center, 5841 S. Maryland Ave., MC-2115, Chicago, IL 60637-1470.

References

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Head and Neck Cancer
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N Engl J Med 1993; 328:1783-1784, Jun 17, 1993. Correspondence

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