To the Editor: The Food and Drug Administration has approvedtwo assays for human immunodeficiency virus (HIV) antibody foruse by "properly trained personnel" in physicians' offices,clinics, emergency rooms, and other settings "where enzyme immunoassaysare not practical or available." The indirect immunofluorescenceand microfiltration enzyme immunoassays are available for purchaseand use in a wide variety of contexts, yet their use raisesserious concern about clinical or operational feasibility andabout their effect on disease-surveillance programs and preventiveintervention.
With respect to clinical usefulness, although the test systemsare accompanied by manufacturers' inserts indicating a needfor retesting . . . [Full Text of this Article]
References
Related Letters:
More on Office-Based Testing for HIV
Frerichs R. R., Seymour E., Mucke H. A.M., Haushofer A., Gellert G., Moore D. F., Greenwood R., Maxwell R. M., Weismuller P. C.
Extract |
Full Text
N Engl J Med 1993;
328:1717-1718, Jun 10, 1993.
Correspondence
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[Abstract]
Frerichs, R. R., Seymour, E., Mucke, H. A.M., Haushofer, A., Gellert, G., Moore, D. F., Greenwood, R., Maxwell, R. M., Weismuller, P. C.
(1993). More on Office-Based Testing for HIV. NEJM
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[Full Text]