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Correspondence
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Volume 328:353-354 February 4, 1993 Number 5
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Genetic Influence on Smoking

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To the Editor: The paper by Carmelli et al. (Sept. 17 issue)1 describing genetic influences on smoking among male subjects in the National Academy of Sciences-National Research Council Twin Registry shows the value of studies of twins in elucidating genetic and environmental influences on important health-related traits and behavior. The large sample provided an opportunity to detect an apparently small but statistically significant excess concordance in monozygotic twins as compared with dizygotic twins, a finding consistent with the existence of genetic influences on this important risk factor. The results of this study must, however, be interpreted with caution. Monozygotic twins . . . [Full Text of this Article]

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