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Previous Volume 328:448 February 11, 1993 Number 6 Next

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By Peter S. Arno and Karyn L. Feiden. 314 pp. New York, HarperCollins, 1992. $23. ISBN 0-06-018309-8.

One of the most profound changes in the American health care system wrought by the AIDS epidemic has been in the drug-development process. In Against the Odds, health economist Peter Arno and health writer Karyn Feiden have written a thorough, well-researched, and easy-to-read history of the first decade of AIDS drug development, a decade that has forever altered the relations among patients, physicians, researchers, the U.S. government, and the pharmaceutical industry.

The book tells the stories of medicines whose time had come (in the opinion of those infected with the human immunodeficiency virus [HIV]) or had not yet come (according . . . [Full Text of this Article]

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