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Previous Volume 328:481 February 18, 1993 Number 7 Next

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Figure 1

View larger version (47K): [in this window] [in a new window]   Figure 1. Membranous Glomerulonephritis. A transmission electron micrograph (Panel A) shows a cross section of a glomerular capillary loop with the typical changes of membranous glomerulonephritis (x5300). Large, electron-dense deposits are visible on the outer aspect of the glomerular basement membrane, with interposition of basement-membrane material that forms "spikes." A fluorescence photomicrograph (Panel B) reveals the IgG composition of these immune deposits within the glomerular capillary wall (x72).

 

Edmund J. Lewis, M.D.
Melvin M. Schwartz, M.D.
Rush-Presbyterian-St. Luke's Medical Center
Chicago, IL 60612

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