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Previous Volume 328:553-559 February 25, 1993 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The solitary thyroid nodule, defined as a palpably discrete swelling within an otherwise apparently normal gland, is usually a benign lesion. However, patient and physician alike are typically concerned about the possibility of thyroid cancer. This review describes a strategy for the treatment of clinically euthyroid patients who have a solitary thyroid nodule that prevents unnecessary testing while identifying the few patients who require therapy. Management has changed in recent years, but important differences of opinion remain over which nodules should be surgically excised. Several recent reviews address these issues comprehensively^1,2,3.

Prevalence of Thyroid Nodules and Cancer

The frequency of thyroid nodules, about half of . . . [Full Text of this Article]

Differential Diagnosis of Thyroid Nodules

Benign Nodules

            Colloid (Adenomatous) Nodules

            Follicular Adenomas

Malignant Nodules

Thyroid Cysts

History and Physical Examination

History

Physical Examination

Laboratory Examination

Fine-Needle Aspiration Biopsy

            Negative Cytologic Results

            Positive Cytologic Results

            Indeterminate Cytologic Results

Imaging Studies

Radionuclide Scanning

Ultrasonography

Natural History

Thyroid Nodules in Children

Therapy

Malignant Lesions

Indeterminate Lesions

Cystic Lesions

Benign Nodules

Conclusions

Source Information

From the Department of Internal Medicine, Ohio State University, 215 Means Hall, 1654 Upham Dr., Columbus, OH 43210-1228, where reprint requests should be addressed to Dr. Mazzaferri.

References

Related Letters:

Solitary Thyroid Nodules
Tong K., Gregerman R. I., Zarkin B. A., Chabot J. A., Gerfo P. L., Mallette L. E., Mazzaferri E. L.
Extract | Full Text  
N Engl J Med 1993; 329:360-361, Jul 29, 1993. Correspondence

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