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Review Article
Drug Therapy
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Volume 328:560-565 February 25, 1993 Number 8
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Hodgkin's Disease
Vincent T. DeVita, and Susan Molloy Hubbard

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Radiotherapy is curative for localized Hodgkin's disease,1,2 and there is now general agreement that advanced Hodgkin's disease can be cured by chemotherapy. This opinion is bolstered by the 20-year survival experience of the original group of patients treated with combination chemotherapy at the National Cancer Institute (Figure 1) and by experience with other regimens (Table 1) 2,3,4,5,6,7,8,9.


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Figure 1. Survival of 188 Patients with Hodgkin's Disease Treated with MOPP (Mechlorethamine, Vincristine, Procarbazine, and Prednisone).

Circles denote patients who relapsed, and vertical lines patients without a relapse. Reprinted from Longo et al.4 with the permission of the publisher.

 
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Table 1. Commonly . . . [Full Text of this Article]

 
Therapy According to Disease Stage

Selecting a Chemotherapy Program

Salvage Treatment

Conclusions


Source Information

From the Memorial Sloan-Kettering Cancer Center, New York (V.T.D.), and the National Cancer Institute, Bethesda, Md. (S.M.H.).

Address reprint requests to Dr. DeVita at the Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021.

References


Related Letters:

Hodgkin's Disease
Perez E. A., Rosenthal S. A., DeVita V. T., Hubbard S. M.
Extract | Full Text  
N Engl J Med 1993; 329:361-362, Jul 29, 1993. Correspondence

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