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Correspondence
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Volume 328:666-667 March 4, 1993 Number 9
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Hypercalcemia in Pregnancy and Lactation Associated with Parathyroid Hormone-Related Protein

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To the Editor: Parathyroid hormone-related protein is produced by tumors associated with hypercalcemia and by a variety of normal tissues including lactating breast tissue1. We describe a woman who had hypercalcemia associated with elevated serum concentrations of parathyroid hormone-related protein during pregnancy and lactation.

Lethargy, thirst, polyuria, and nocturia developed in a 34-year-old woman who was 35 weeks pregnant. Physical examination was normal. Her serum calcium concentration was 11.9 mg per deciliter (normal, 9.0 to 10.4) initially and 14.0 mg per deciliter at delivery at 38 weeks of gestation. The serum parathyroid hormone concentration was low. No evidence of . . . [Full Text of this Article]

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