To the Editor: Parathyroid hormone-related protein is producedby tumors associated with hypercalcemia and by a variety ofnormal tissues including lactating breast tissue1. We describea woman who had hypercalcemia associated with elevated serumconcentrations of parathyroid hormone-related protein duringpregnancy and lactation.
Lethargy, thirst, polyuria, and nocturia developed in a 34-year-oldwoman who was 35 weeks pregnant. Physical examination was normal.Her serum calcium concentration was 11.9 mg per deciliter (normal,9.0 to 10.4) initially and 14.0 mg per deciliter at deliveryat 38 weeks of gestation. The serum parathyroid hormone concentrationwas low. No evidence of . . . [Full Text of this Article]
References
This article has been cited by other articles:
Jacobs, T. P., Bilezikian, J. P.
(2005). Rare Causes of Hypercalcemia. J. Clin. Endocrinol. Metab.
90: 6316-6322
[Abstract][Full Text]
Strewler, G. J.
(2000). The Physiology of Parathyroid Hormone-Related Protein. NEJM
342: 177-185
[Full Text]
Mather, K. J., Chik, C. L., Corenblum, B.
(1999). Maintenance of Serum Calcium by Parathyroid Hormone-Related Peptide During Lactation in a Hypoparathyroid Patient. J. Clin. Endocrinol. Metab.
84: 424-427
[Abstract][Full Text]
Guise, T. A., Mundy, G. R.
(1998). Cancer and Bone. Endocr. Rev.
19: 18-54
[Abstract][Full Text]
Kovacs, C. S., Kronenberg, H. M.
(1997). Maternal-Fetal Calcium and Bone Metabolism During Pregnancy, Puerperium, and Lactation. Endocr. Rev.
18: 832-872
[Abstract][Full Text]