FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 329:31-37 July 1, 1993 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

The growing popularity of travel to the tropics (more than 9 million tourists arrive in Africa each year and more than 32 million in Asia and the southwestern Pacific region¹) is placing an increasing number of travelers at risk for acquiring malaria. The number of cases of imported malaria reported annually to health authorities (approximately 1000 in the United States and several thousand in Europe) underestimates the problem,^2,3 in large part because it does not include travelers who become sick while abroad. Delayed diagnosis and inadequate treatment of imported cases of malaria caused by Plasmodium falciparum have resulted in . . . [Full Text of this Article]

The Life Cycle of Plasmodium

Estimating the Risk of Malaria in Travelers

Malaria Prophylaxis: High Levels of Confusion and Low Levels of Compliance

Strategies for Malaria Prevention

Antimosquito Measures

Chemoprophylactic Regimens

Mefloquine

Doxycycline

Chloroquine

Chloroguanide Hydrochloride

Primaquine

Other Prophylactic Regimens and Self-Treatment Agents

Pyrimethamine-Sulfadoxine and Pyrimethamine-Dapsone Combinations

Halofantrine

Prophylaxis in Pregnant Women and Children

The Future

Source Information

From the Division of Geographic Medicine and Infectious Diseases, Department of Medicine, New England Medical Center Hospital and Tufts University School of Medicine, Boston.

Address reprint requests to Dr. Wyler at the New England Medical Center Hospitals, 750 Washington St., Box 041, Boston, MA 02111.

References

This article has been cited by other articles:

• Binh, V. Q., Chinh, N. T., Thanh, N. X., Cuong, B. T., Quang, N. N., Dai, B., Travers, T., Edstein, M. D. (2009). Sex Affects the Steady-State Pharmacokinetics of Primaquine but Not Doxycycline in Healthy Subjects. Am J Trop Med Hyg 81: 747-753 [Abstract] [Full Text]  
• Fiaccadori, E., Maggiore, U., Rotelli, C., Giacosa, R., Parenti, E., Cabassi, A., Ariya, K., Wirote, L. (2006). Thrombotic-thrombocytopenic purpura following malaria prophylaxis with mefloquine. J Antimicrob Chemother 57: 160-161 [Full Text]  
• Youle, M., Wainberg, M. A. (2003). Pre-Exposure Chemoprophylaxis (PREP) as an HIV Prevention Strategy. J Int Assoc Physicians AIDS Care (Chic Ill) 2: 102-105 [Abstract]  
• Ryan, E. T., Kain, K. C. (2000). Health Advice and Immunizations for Travelers. NEJM 342: 1716-1725 [Full Text]  
• Viani, R. M., Bromberg, K. (1999). Pediatric Imported Malaria in New York: Delayed Diagnosis. CLIN PEDIATR 38: 333-337 [Abstract]  
• Lobel, H. O., Kozarsky, P. E. (1997). Update on Prevention of Malaria for Travelers. JAMA 278: 1767-1771 [Abstract]  
• Liu, L. X., Weller, P. F. (1996). Antiparasitic Drugs. NEJM 334: 1178-1184 [Full Text]  
• Magill, A. J., Smoak, B. L. (1993). Failure of Mefloquine Chemoprophylaxis for Malaria in Somalia. NEJM 329: 1206-1206 [Full Text]  
• Su, Y., Zharikov, S. I., Block, E. R. (2002). Microtubule-active agents modify nitric oxide production in pulmonary artery endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 282: L1183-L1189 [Abstract] [Full Text]