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The history of vasculitis is replete with redefinition, "evolution," and recategorization. In the past few years, such changes have been promoted by the recognition of antineutrophil cytoplasmic autoantibodies, which are found in the blood of patients with various types of vasculitis as well as necrotizing glomerulonephritis. This subject and the role of the neutrophil in systemic vasculitis are clinically relevant and well addressed in one of the chapters in Systemic Vasculitis. Other areas covered in the book include the role of vascular endothelium in the pathogenesis of vasculitis, lymphocyte-endothelium interactions, and the role of monocytes, macrophages, and mast cells in
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