The post-traumatic fat embolism syndrome is a multisystem disordercharacterized by pulmonary and neurologic dysfunction, pyrexia,and a petechial rash1,2,3,4. More than a century after the firstdescriptions of the fat embolism syndrome, the cause of fatemboli and the pathogenesis of the systemic manifestations ofthis disorder remain incompletely understood. We describe apatient undergoing treatment of a femoral fracture in whom massivefat embolism was demonstrated by transesophageal echocardiography.Acute cor pulmonale developed, precipitating paradoxical fatembolism across a patent foramen ovale, with the subsequentdevelopment of the fat embolism syndrome. Embolism of fat acrossa patent . . . [Full Text of this Article]
Case Report
Discussion
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From the Departments of Cardiology (A.C.H.P., G.R.S.), Pathology (D.H., A.B.), and Orthopaedic Surgery (J.K., J.C.), Royal Infirmary, Edinburgh, United Kingdom. Presented in part at the 42nd annual scientific session of the American College of Cardiology, Anaheim, Calif., March 14-18, 1993.
Address reprint requests to Dr. Pell at the Department of Cardiology, Western Infirmary, Glasgow G11 6NT, United Kingdom.
References
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Fat Embolism Syndrome
Parmet J. L., Horrow J., Rosenberg H., Haller M., Schelling G., Pell A. C.H., Christie J.
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N Engl J Med 1994;
330:642-643, Mar 3, 1994.
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