In the United States, more vector-borne diseases are transmittedby ticks than by any other agent1. During the past 20 years,tick-borne diseases have taken on increased importance as humanshave moved into rural areas and increased their recreationaloutdoor activity. Tick-borne diseases can result from infectionwith pathogens that include bacteria, rickettsia, viruses, andprotozoa (Table 1). In this article, we review recent advancesin the understanding of these diseases, particularly the microbiology,epidemiology, diagnosis, and treatment of the major tick-bornediseases that occur in the United States.
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Table 1. Major Tick-Borne Diseases in the United States.
From the Division of Infectious Diseases, Department of Medicine (D.H.S., W.C.L.), and the Division of Clinical Microbiology (T.R.F.), University of Washington, Seattle; the Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colo. (G.L.C.); the Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta (R.E.Q.); and the Division of Laboratory Medicine, Sacred Heart Medical Center, Spokane, Wash. (D.A.E.).
Address reprint requests to Dr. Spach at the Madison Clinic, ZA-09, 1001 Broadway, Suite 206, Seattle, WA 98122.
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