FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 329:1001-1006 September 30, 1993 Number 14 Next

	Full Text Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

ABSTRACT

Background Among patients with end-stage renal disease who are treated with hemodialysis, solute clearance during dialysis and nutritional adequacy are determinants of mortality. We determined the effects of reductions in blood urea nitrogen concentrations during dialysis and changes in serum albumin concentrations, as an indicator of nutritional status, on mortality in a large group of patients treated with hemodialysis.

Methods We analyzed retrospectively the demographic characteristics, mortality rate, duration of hemodialysis, serum albumin concentration, and urea reduction ratio (defined as the percent reduction in blood urea nitrogen concentration during a single dialysis treatment) in 13,473 patients treated from October 1, 1990, through March 31, 1991. The risk of death was determined as a function of the urea reduction ratio and serum albumin concentration.

Results As compared with patients with urea reduction ratios of 65 to 69 percent, patients with values below 60 percent had a higher risk of death during follow-up (odds ratio, 1.28 for urea reduction ratios of 55 to 59 percent and 1.39 for ratios below 55 percent). Fifty-five percent of the patients had urea reduction ratios below 60 percent. The duration of dialysis was not predictive of mortality. The serum albumin concentration was a more powerful (21 times greater) predictor of death than the urea reduction ratio, and 60 percent of the patients had serum albumin concentrations predictive of an increased risk of death (values below 4.0 g per deciliter). The odds ratio for death was 1.48 for serum albumin concentrations of 3.5 to 3.9 g per deciliter and 3.13 for concentrations of 3.0 to 3.4 g per deciliter. Diabetic patients had lower serum albumin concentrations and urea reduction ratios than nondiabetic patients.

Conclusions Low urea reduction ratios during dialysis are associated with increased odds ratios for death. These risks are worsened by inadequate nutrition.

Source Information

From Brigham and Women's Hospital and Harvard Medical School, Boston (W.F.O., J.M.L.), and National Medical Care, Inc. (a subsidiary of W.R. Grace & Co.), Waltham, Mass. (N.L.L., Y.L., E.G.L.).

Address reprint requests to Dr. Owen at the Seeley Mudd Bldg., Brigham and Women's Hospital, 250 Longwood Ave., Boston, MA 02115.

Full Text of this Article

Related Letters:

Predictors of Mortality in Patients Undergoing Hemodialysis
Hensrud D. D., McMahon M. M., Cohen E. P., Owen W. F.
Extract | Full Text  
N Engl J Med 1994; 330:573-574, Feb 24, 1994. Correspondence

This article has been cited by other articles:

• Vonesh, E. (2009). ON SMALL SOLUTE CLEARANCE AND PATIENT OUTCOMES: EVIDENTIAL PRACTICE OR OBSERVATIONAL TREPIDATION?. pdi 29: 623-629 [Abstract] [Full Text]  
• Pellicano, R., Strauss, B. J., Polkinghorne, K. R., Kerr, P. G. (2009). Body composition in home haemodialysis versus conventional haemodialysis: a cross-sectional, matched, comparative study. Nephrol Dial Transplant 0: gfp490v1-gfp490 [Abstract] [Full Text]  
• Heng, A.-E., Cano, N. J. M. (2009). A general overview of malnutrition in normal kidney function and in chronic kidney disease. NDT Plus 0: sfp128v1-sfp128 [Full Text]  
• Patel, R. K., Oliver, S., Mark, P. B., Powell, J. R., McQuarrie, E. P., Traynor, J. P., Dargie, H. J., Jardine, A. G. (2009). Determinants of Left Ventricular Mass and Hypertrophy in Hemodialysis Patients Assessed by Cardiac Magnetic Resonance Imaging. CJASN 4: 1477-1483 [Abstract] [Full Text]  
• Argyropoulos, C., Chang, C.-C. H., Plantinga, L., Fink, N., Powe, N., Unruh, M. (2009). Considerations in the Statistical Analysis of Hemodialysis Patient Survival. J. Am. Soc. Nephrol. 20: 2034-2043 [Abstract] [Full Text]  
• Brunelli, S. M. (2009). Measuring Patient Survival on Hemodialysis. J. Am. Soc. Nephrol. 20: 1866-1867 [Full Text]  
• Segall, L., Mardare, N.-G., Ungureanu, S., Busuioc, M., Nistor, I., Enache, R., Marian, S., Covic, A. (2009). Nutritional status evaluation and survival in haemodialysis patients in one centre from Romania. Nephrol Dial Transplant 24: 2536-2540 [Abstract] [Full Text]  
• de Bie, M. K., van Dam, B., Gaasbeek, A., van Buren, M., van Erven, L., Bax, J. J., Schalij, M. J., Rabelink, T. J., Jukema, J. W. (2009). The current status of interventions aiming at reducing sudden cardiac death in dialysis patients. Eur Heart J 30: 1559-1564 [Abstract] [Full Text]  
• Lee, P.-S., Sampath, K., Karumanchi, S. A., Tamez, H., Bhan, I., Isakova, T., Gutierrez, O. M., Wolf, M., Chang, Y., Stossel, T. P., Thadhani, R. (2009). Plasma Gelsolin and Circulating Actin Correlate with Hemodialysis Mortality. J. Am. Soc. Nephrol. 20: 1140-1148 [Abstract] [Full Text]  
• Couchoud, C., Jager, K. J., Tomson, C., Cabanne, J.-F., Collart, F., Finne, P., de Francisco, A., Frimat, L., Garneata, L., Leivestad, T., Lemaitre, V., Limido, A., Ots, M., Resic, H., Stojceva-Taneva, O., Kooman, J., On behalf of the QUEST working group on dialysis a, (2009). Assessment of urea removal in haemodialysis and the impact of the European Best Practice Guidelines. Nephrol Dial Transplant 24: 1267-1274 [Abstract] [Full Text]  
• Chan, K. E., Lazarus, J. M., Thadhani, R., Hakim, R. M. (2009). Anticoagulant and Antiplatelet Usage Associates with Mortality among Hemodialysis Patients. J. Am. Soc. Nephrol. 20: 872-881 [Abstract] [Full Text]  
• Doumas, B. T., Peters, T. Jr. (2009). Origins of Dye-Binding Methods for Measuring Serum Albumin. Clin. Chem. 55: 583-584 [Full Text]  
• Hasegawa, T., Bragg-Gresham, J. L., Yamazaki, S., Fukuhara, S., Akizawa, T., Kleophas, W., Greenwood, R., Pisoni, R. L. (2009). Greater First-Year Survival on Hemodialysis in Facilities in Which Patients Are Provided Earlier and More Frequent Pre-nephrology Visits. CJASN 4: 595-602 [Abstract] [Full Text]  
• Locatelli, F., Martin-Malo, A., Hannedouche, T., Loureiro, A., Papadimitriou, M., Wizemann, V., Jacobson, S. H., Czekalski, S., Ronco, C., Vanholder, R., for the Membrane Permeability Outcome (MPO) Study, (2009). Effect of Membrane Permeability on Survival of Hemodialysis Patients. J. Am. Soc. Nephrol. 20: 645-654 [Abstract] [Full Text]  
• Rabbani, N., Thornalley, P. J. (2009). QUANTITATION OF MARKERS OF PROTEIN DAMAGE BY GLYCATION, OXIDATION, AND NITRATION IN PERITONEAL DIALYSIS. pdi 29: S51-S56 [Abstract] [Full Text]  
• Saudan, P., Kossovsky, M., Halabi, G., Martin, P. Y., Perneger, T. V., for the Western Switzerland Dialysis Study Group, (2008). Quality of care and survival of haemodialysed patients in western Switzerland. Nephrol Dial Transplant 23: 1975-1981 [Abstract] [Full Text]  
• Amaral, S., Hwang, W., Fivush, B., Neu, A., Frankenfield, D., Furth, S. (2008). Serum Albumin Level and Risk for Mortality and Hospitalization in Adolescents on Hemodialysis. CJASN 3: 759-767 [Abstract] [Full Text]  
• Burt, M. G., Johannsson, G., Umpleby, A. M., Chisholm, D. J., Ho, K. K. Y. (2008). Impact of Growth Hormone and Dehydroepiandrosterone on Protein Metabolism in Glucocorticoid-Treated Patients. J. Clin. Endocrinol. Metab. 93: 688-695 [Abstract] [Full Text]  
• Kojima, M., Hayano, J., Fukuta, H., Sakata, S., Mukai, S., Ohte, N., Seno, H., Toriyama, T., Kawahara, H., Furukawa, T. A., Tokudome, S. (2008). Loss of Fractal Heart Rate Dynamics in Depressive Hemodialysis Patients. Psychosom. Med. 70: 177-185 [Abstract] [Full Text]  
• Fong, E., Bargman, J. M., Chan, C. T. (2007). Cross-Sectional Comparison of Quality of Life and Illness Intrusiveness in Patients Who Are Treated with Nocturnal Home Hemodialysis versus Peritoneal Dialysis. CJASN 2: 1195-1200 [Abstract] [Full Text]  
• Burt, M. G., Johannsson, G., Umpleby, A. M., Chisholm, D. J., Ho, K. K. Y. (2007). Impact of Acute and Chronic Low-Dose Glucocorticoids on Protein Metabolism. J. Clin. Endocrinol. Metab. 92: 3923-3929 [Abstract] [Full Text]  
• Kovesdy, C. P., Regidor, D. L., Mehrotra, R., Jing, J., McAllister, C. J., Greenland, S., Kopple, J. D., Kalantar-Zadeh, K. (2007). Serum and Dialysate Potassium Concentrations and Survival in Hemodialysis Patients. CJASN 2: 999-1007 [Abstract] [Full Text]  
• Cano, N. J.M., Fouque, D., Roth, H., Aparicio, M., Azar, R., Canaud, B., Chauveau, P., Combe, C., Laville, M., Leverve, X. M., the French Study Group for Nutrition in Dialysis, (2007). Intradialytic Parenteral Nutrition Does Not Improve Survival in Malnourished Hemodialysis Patients: A 2-Year Multicenter, Prospective, Randomized Study. J. Am. Soc. Nephrol. 18: 2583-2591 [Abstract] [Full Text]  
• Tentori, F., Hunt, W. C., Rohrscheib, M., Zhu, M., Stidley, C. A., Servilla, K., Miskulin, D., Meyer, K. B., Bedrick, E. J., Johnson, H. K., Zager, P. G. (2007). Which Targets in Clinical Practice Guidelines Are Associated with Improved Survival in a Large Dialysis Organization?. J. Am. Soc. Nephrol. 18: 2377-2384 [Abstract] [Full Text]  
• Liu, J.-H., Lin, P.-W., Liu, Y.-L., Lin, H.-H., Huang, C.-C. (2007). Comparison of classical and non-classical cardiovascular risk factors influencing the patency of native arteriovenous fistulas after percutaneous transluminal angioplasty therapy among haemodialysis patients. Postgrad. Med. J. 83: 547-551 [Abstract] [Full Text]  
• Ajiro, J., Alchi, B., Narita, I., Omori, K., Kondo, D., Sakatsume, M., Kazama, J. J., Akazawa, K., Gejyo, F. (2007). Mortality Predictors after 10 Years of Dialysis: A Prospective Study of Japanese Hemodialysis Patients. CJASN 2: 653-660 [Abstract] [Full Text]  
• Feldt-Rasmussen, B., Lange, M., Sulowicz, W., Gafter, U., Lai, K. N., Wiedemann, J., Christiansen, J. S., El Nahas, M., and the Adult Patients in Chronic Dialysis (APCD), (2007). Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life, and Cardiovascular Risk. J. Am. Soc. Nephrol. 18: 2161-2171 [Abstract] [Full Text]  
• Burt, M. G., Gibney, J., Ho, K. K. Y. (2007). Protein metabolism in glucocorticoid excess: study in Cushing's syndrome and the effect of treatment. Am. J. Physiol. Endocrinol. Metab. 292: E1426-E1432 [Abstract] [Full Text]  
• Kshirsagar, A. V., Craig, R. G., Beck, J. D., Moss, K., Offenbacher, S., Kotanko, P., Yoshino, M., Levin, N. W., Yip, J. K., Almas, K., Lupovici, E., Falk, R. J. (2007). Severe Periodontitis Is Associated with Low Serum Albumin among Patients on Maintenance Hemodialysis Therapy. CJASN 2: 239-244 [Abstract] [Full Text]  
• Kilpatrick, R. D., McAllister, C. J., Kovesdy, C. P., Derose, S. F., Kopple, J. D., Kalantar-Zadeh, K. (2007). Association between Serum Lipids and Survival in Hemodialysis Patients and Impact of Race. J. Am. Soc. Nephrol. 18: 293-303 [Abstract] [Full Text]  
• Rocco, M. V., Frankenfield, D. L., Hopson, S. D., McClellan, W. M. (2006). Relationship between clinical performance measures and outcomes among patients receiving long-term hemodialysis.. ANN INTERN MED 145: 512-519 [Abstract] [Full Text]  
• Amaral, S., Hwang, W., Fivush, B., Neu, A., Frankenfield, D., Furth, S. (2006). Association of Mortality and Hospitalization with Achievement of Adult Hemoglobin Targets in Adolescents Maintained on Hemodialysis. J. Am. Soc. Nephrol. 17: 2878-2885 [Abstract] [Full Text]  
• Joki, N., Hase, H., Tanaka, Y., Takahashi, Y., Saijyo, T., Ishikawa, H., Inishi, Y., Imamura, Y., Hara, H., Tsunoda, T., Nakamura, M. (2006). Relationship between serum albumin level before initiating haemodialysis and angiographic severity of coronary atherosclerosis in end-stage renal disease patients. Nephrol Dial Transplant 21: 1633-1639 [Abstract] [Full Text]  
• Ricci, Z., Bellomo, R., Ronco, C. (2006). Dose of Dialysis in Acute Renal Failure. CJASN 1: 380-388 [Full Text]  
• Bellizzi, V., Scalfi, L., Terracciano, V., De Nicola, L., Minutolo, R., Marra, M., Guida, B., Cianciaruso, B., Conte, G., Di Iorio, B. R. (2006). Early Changes in Bioelectrical Estimates of Body Composition in Chronic Kidney Disease. J. Am. Soc. Nephrol. 17: 1481-1487 [Abstract] [Full Text]  
• Jindal, K., Chan, C. T., Deziel, C., Hirsch, D., Soroka, S. D., Tonelli, M., Culleton, B. F. (2006). CHAPTER 1: Hemodialysis Adequacy in Adults. J. Am. Soc. Nephrol. 17: S4-S7 [Full Text]  
• Jindal, K., Chan, C. T., Deziel, C., Hirsch, D., Soroka, S. D., Tonelli, M., Culleton, B. F. (2006). CHAPTER 5: Frequent and Sustained Hemodialysis. J. Am. Soc. Nephrol. 17: S24-S27 [Full Text]  
• Wu, D. Y., Shinaberger, C. S., Regidor, D. L., McAllister, C. J., Kopple, J. D., Kalantar-Zadeh, K. (2006). Association between Serum Bicarbonate and Death in Hemodialysis Patients: Is It Better to Be Acidotic or Alkalotic?. CJASN 1: 70-78 [Abstract] [Full Text]  
• Traynor, J. P., Oun, H. A., McKenzie, P., Shilliday, I. R., McKay, I. G., Dunlop, A., Geddes, C. C., Mactier, R. A. (2005). Assessing the utility of the stop dialysate flow method in patients receiving haemodiafiltration. Nephrol Dial Transplant 20: 2479-2484 [Abstract] [Full Text]  
• Greene, T., Daugirdas, J., Depner, T., Allon, M., Beck, G., Chumlea, C., Delmez, J., Gotch, F., Kusek, J. W., Levin, N., Owen, W., Schulman, G., Star, R., Toto, R., Eknoyan, G., for the Hemodialysis Study Group, (2005). Association of Achieved Dialysis Dose with Mortality in the Hemodialysis Study: An Example of "Dose-Targeting Bias". J. Am. Soc. Nephrol. 16: 3371-3380 [Abstract] [Full Text]  
• Kalantar-Zadeh, K., Regidor, D. L., McAllister, C. J., Michael, B., Warnock, D. G. (2005). Time-Dependent Associations between Iron and Mortality in Hemodialysis Patients. J. Am. Soc. Nephrol. 16: 3070-3080 [Abstract] [Full Text]  
• Chan, C. T., Li, S. H., Verma, S. (2005). Nocturnal hemodialysis is associated with restoration of impaired endothelial progenitor cell biology in end-stage renal disease. Am. J. Physiol. Renal Physiol. 289: F679-F684 [Abstract] [Full Text]  
• Ward, R. A. (2005). Protein-Leaking Membranes for Hemodialysis: A New Class of Membranes in Search of an Application?. J. Am. Soc. Nephrol. 16: 2421-2430 [Abstract] [Full Text]  
• Andreoli, S. P., Brewer, E. D., Watkins, S., Fivush, B., Powe, N., Shevchek, J., Foreman, J. (2005). American Society of Pediatric Nephrology Position Paper on Linking Reimbursement to Quality of Care. J. Am. Soc. Nephrol. 16: 2263-2269 [Full Text]  
• Wynne, K., Giannitsopoulou, K., Small, C. J., Patterson, M., Frost, G., Ghatei, M. A., Brown, E. A., Bloom, S. R., Choi, P. (2005). Subcutaneous Ghrelin Enhances Acute Food Intake in Malnourished Patients Who Receive Maintenance Peritoneal Dialysis: A Randomized, Placebo-Controlled Trial. J. Am. Soc. Nephrol. 16: 2111-2118 [Abstract] [Full Text]  
• Seres, D. S. (2005). Surrogate Nutrition Markers, Malnutrition, and Adequacy of Nutrition Support. Nutr Clin Pract 20: 308-313 [Abstract] [Full Text]  
• Manhes, G., Heng, A. E., Aublet-Cuvelier, B., Gazuy, N., Deteix, P., Souweine, B. (2005). Clinical features and outcome of chronic dialysis patients admitted to an intensive care unit. Nephrol Dial Transplant 20: 1127-1133 [Abstract] [Full Text]  
• Allon, M., Radeva, M., Bailey, J., Beddhu, S., Butterly, D., Coyne, D. W., Depner, T. A., Gassman, J. J., Kaufman, A. M., Kaysen, G. A., Lewis, J. A., Schwab, S. J., for the HEMO Study Group, (2005). The spectrum of infection-related morbidity in hospitalized haemodialysis patients. Nephrol Dial Transplant 20: 1180-1186 [Abstract] [Full Text]  
• Agalou, S., Ahmed, N., Babaei-Jadidi, R., Dawnay, A., Thornalley, P. J. (2005). Profound Mishandling of Protein Glycation Degradation Products in Uremia and Dialysis. J. Am. Soc. Nephrol. 16: 1471-1485 [Abstract] [Full Text]  
• Kamimura, M. A., Majchrzak, K. M., Cuppari, L., Pupim, L. B. (2005). Protein and Energy Depletion in Chronic Hemodialysis Patients: Clinical Applicability of Diagnostic Tools. Nutr Clin Pract 20: 162-175 [Abstract] [Full Text]  
• Plantinga, L. C., Jaar, B. G., Fink, N. E., Sadler, J. H., Levin, N. W., Coresh, J., Klag, M. J., Powe, N. R. (2005). Frequency of patient-physician contact in chronic kidney disease care and achievement of clinical performance targets. Int J Qual Health Care 17: 115-121 [Abstract] [Full Text]  
• Kalantar-Zadeh, K., Kilpatrick, R. D., McAllister, C. J., Greenland, S., Kopple, J. D. (2005). Reverse Epidemiology of Hypertension and Cardiovascular Death in the Hemodialysis Population: The 58th Annual Fall Conference and Scientific Sessions. Hypertension 45: 811-817 [Abstract] [Full Text]  
• Locatelli, F., Buoncristiani, U., Canaud, B., Kohler, H., Petitclerc, T., Zucchelli, P. (2005). Dialysis dose and frequency. Nephrol Dial Transplant 20: 285-296 [Abstract] [Full Text]  
• Grooteman, M. P. C., Nube, M. J. (2004). Impact of the type of dialyser on the clinical outcome in chronic haemodialysis patients: does it really matter?. Nephrol Dial Transplant 19: 2965-2970 [Full Text]  
• Plantinga, L. C., Fink, N. E., Jaar, B. G., Sadler, J. H., Coresh, J., Klag, M. J., Levey, A. S., Powe, N. R. (2004). Frequency of Sit-Down Patient Care Rounds, Attainment of Clinical Performance Targets, Hospitalization, and Mortality in Hemodialysis Patients. J. Am. Soc. Nephrol. 15: 3144-3153 [Abstract] [Full Text]  
• Sambrook, P. N., Chen, J. S., March, L. M., Cameron, I. D., Cumming, R. G., Lord, S. R., Schwarz, J., Seibel, M. J. (2004). Serum Parathyroid Hormone Is Associated with Increased Mortality Independent of 25-Hydroxy Vitamin D Status, Bone Mass, and Renal Function in the Frail and Very Old: A Cohort Study. J. Clin. Endocrinol. Metab. 89: 5477-5481 [Abstract] [Full Text]  
• Chiang, C.-K., Hsu, S.-P., Pai, M.-F., Peng, Y.-S., Ho, T.-I, Liu, S.-H., Hung, K.-Y., Tsai, T.-J. (2004). Interleukin-18 is a strong predictor of hospitalization in haemodialysis patients. Nephrol Dial Transplant 19: 2810-2815 [Abstract] [Full Text]  
• Dara, S. I., Afessa, B., Bajwa, A. A., Albright, R. C. (2004). Outcome of Patients With End-Stage Renal Disease Admitted to the Intensive Care Unit. Mayo Clin Proc. 79: 1385-1390 [Abstract]  
• Wiederkehr, M. R., Kalogiros, J., Krapf, R. (2004). Correction of metabolic acidosis improves thyroid and growth hormone axes in haemodialysis patients. Nephrol Dial Transplant 19: 1190-1197 [Abstract] [Full Text]  
• Kloppenburg, W. D., Stegeman, C. A., Kremer Hovinga, T. K., Vastenburg, G., Vos, P., de Jong, P. E., Huisman, R. M. (2004). Effect of prescribing a high protein diet and increasing the dose of dialysis on nutrition in stable chronic haemodialysis patients: a randomized, controlled trial. Nephrol Dial Transplant 19: 1212-1223 [Abstract] [Full Text]  
• Termorshuizen, F., Dekker, F. W., van Manen, J. G., Korevaar, J. C., Boeschoten, E. W., Krediet, R. T. (2004). Relative Contribution of Residual Renal Function and Different Measures of Adequacy to Survival in Hemodialysis Patients: An analysis of the Netherlands Cooperative Study on the Adequacy of Dialysis (NECOSAD)-2. J. Am. Soc. Nephrol. 15: 1061-1070 [Abstract] [Full Text]  
• McClellan, W. M., Hodgin, E., Pastan, S., McAdams, L., Soucie, M. (2004). A Randomized Evaluation of Two Health Care Quality Improvement Program (HCQIP) Interventions to Improve the Adequacy of Hemodialysis Care of ESRD Patients: Feedback Alone versus Intensive Intervention. J. Am. Soc. Nephrol. 15: 754-760 [Abstract] [Full Text]  
• Lambie, S. H., Taal, M. W., Fluck, R. J., McIntyre, C. W. (2004). Analysis of factors associated with variability in haemodialysis adequacy. Nephrol Dial Transplant 19: 406-412 [Abstract] [Full Text]  
• Metcalfe, W., Khan, I.H., Prescott, G.J., Simpson, K., Macleod, A.M. (2003). Hospitalization in the first year of renal replacement therapy for end-stage renal disease. QJM 96: 899-909 [Abstract] [Full Text]  
• Cheung, A. K., Levin, N. W., Greene, T., Agodoa, L., Bailey, J., Beck, G., Clark, W., Levey, A. S., Leypoldt, J. K., Ornt, D. B., Rocco, M. V., Schulman, G., Schwab, S., Teehan, B., Eknoyan, G. (2003). Effects of High-Flux Hemodialysis on Clinical Outcomes: Results of the HEMO Study. J. Am. Soc. Nephrol. 14: 3251-3263 [Abstract] [Full Text]  
• Brimble, K. S., Treleaven, D. J., Onge, J. S., Carlisle, E. J. (2003). Risk factors for increased variability in dialysis delivery in haemodialysis patients. Nephrol Dial Transplant 18: 2112-2117 [Abstract] [Full Text]  
• Szczech, L. A., Reddan, D. N., Klassen, P. S., Coladonato, J., Chua, B., Lowrie, E. G., Lazarus, J. M., Owen, W. F. Jr (2003). Interactions between dialysis-related volume exposures, nutritional surrogates and mortality among ESRD patients. Nephrol Dial Transplant 18: 1585-1591 [Abstract] [Full Text]  
• Szczech, L. A., Reddan, D. N., Klassen, P. S., Coladonato, J., Chua, B., Lowrie, E. G., Lazarus, J. M., Owen, W. F. Jr (2003). Interactions between dialysis-related volume exposures, nutritional surrogates and mortality among ESRD patients. Nephrol Dial Transplant 18: 1585-1591 [Abstract] [Full Text]  
• Teng, M., Wolf, M., Lowrie, E., Ofsthun, N., Lazarus, J. M., Thadhani, R. (2003). Survival of Patients Undergoing Hemodialysis with Paricalcitol or Calcitriol Therapy. NEJM 349: 446-456 [Abstract] [Full Text]  
• Wang, A. Y.-M., Woo, J., Lam, C. W.-K., Wang, M., Sea, M. M.-M., Lui, S.-F., Li, P. K.-T., Sanderson, J. (2003). Is a Single Time Point C-Reactive Protein Predictive of Outcome in Peritoneal Dialysis Patients?. J. Am. Soc. Nephrol. 14: 1871-1879 [Abstract] [Full Text]  
• Ono, K., Tsuchida, A., Kawai, H., Matsuo, H., Wakamatsu, R., Maezawa, A., Yano, S., Kawada, T., Nojima, Y. (2003). Ankle-Brachial Blood Pressure Index Predicts All-Cause and Cardiovascular Mortality in Hemodialysis Patients. J. Am. Soc. Nephrol. 14: 1591-1598 [Abstract] [Full Text]  
• Teehan, G. S., Liangos, O., Jaber, B. L. (2003). Update on Dialytic Management of Acute Renal Failure. J Intensive Care Med 18: 130-138 [Abstract]  
• Rodriguez, R. A., Mendelson, M., O'Hare, A. M., Hsu, L. C., Schoenfeld, P. (2003). Determinants of Survival among HIV-Infected Chronic Dialysis Patients. J. Am. Soc. Nephrol. 14: 1307-1313 [Abstract] [Full Text]  
• McIntyre, C. W., Lambie, S. H., Taal, M. W., Fluck, R. J. (2003). Assessment of haemodialysis adequacy by ionic dialysance: intra-patient variability of delivered treatment. Nephrol Dial Transplant 18: 559-562 [Abstract] [Full Text]  
• Sehgal, A. R. (2003). Impact of Quality Improvement Efforts on Race and Sex Disparities in Hemodialysis. JAMA 289: 996-1000 [Abstract] [Full Text]  
• Eknoyan, G., Beck, G. J., Cheung, A. K., Daugirdas, J. T., Greene, T., Kusek, J. W., Allon, M., Bailey, J., Delmez, J. A., Depner, T. A., Dwyer, J. T., Levey, A. S., Levin, N. W., Milford, E., Ornt, D. B., Rocco, M. V., Schulman, G., Schwab, S. J., Teehan, B. P., Toto, R., the Hemodialysis (HEMO) Study Group, (2002). Effect of Dialysis Dose and Membrane Flux in Maintenance Hemodialysis. NEJM 347: 2010-2019 [Abstract] [Full Text]  
• Kinchen, K. S., Sadler, J., Fink, N., Brookmeyer, R., Klag, M. J., Levey, A. S., Powe, N. R. (2002). The Timing of Specialist Evaluation in Chronic Kidney Disease and Mortality. ANN INTERN MED 137: 479-486 [Abstract] [Full Text]  
• Williams, D. M., Sreedhar, S. S., Mickell, J. J., Chan, J. C. M. (2002). Acute Kidney Failure: A Pediatric Experience Over 20 Years. Arch Pediatr Adolesc Med 156: 893-900 [Abstract] [Full Text]  
• Fink, J. C., Zhan, M., Blahut, S. A., Soucie, M., McClellan, W. M. (2002). Measuring the Efficacy of a Quality Improvement Program in Dialysis Adequacy with Changes in Center Effects. J. Am. Soc. Nephrol. 13: 2338-2344 [Abstract] [Full Text]  
• Winkelmayer, W. C., Glynn, R. J., Mittleman, M. A., Levin, R., Pliskin, J. S., Avorn, J. (2002). Comparing Mortality of Elderly Patients on Hemodialysis versus Peritoneal Dialysis: A Propensity Score Approach. J. Am. Soc. Nephrol. 13: 2353-2362 [Abstract] [Full Text]  
• Brimble, K. S., Onge, J. S., Treleaven, D. J., Carlisle, E. J. (2002). Comparison of volume of blood processed on haemodialysis adequacy measurement sessions vs regular non-adequacy sessions. Nephrol Dial Transplant 17: 1470-1474 [Abstract] [Full Text]  
• Port, F. K., Ashby, V. B., Dhingra, R. K., Roys, E. C., Wolfe, R. A. (2002). Dialysis Dose and Body Mass Index Are Strongly Associated with Survival in Hemodialysis Patients. J. Am. Soc. Nephrol. 13: 1061-1066 [Abstract] [Full Text]  
• Qureshi, A. R., Alvestrand, A., Divino-Filho, J. C., Gutierrez, A., Heimburger, O., Lindholm, B., Bergstrom, J. (2002). Inflammation, Malnutrition, and Cardiac Disease as Predictors of Mortality in Hemodialysis Patients. J. Am. Soc. Nephrol. 13: S28-36 [Abstract] [Full Text]  
• Keshaviah, P., Collins, A. J., Ma, J. Z., Churchill, D. N., Thorpe, K. E. (2002). Survival Comparison between Hemodialysis and Peritoneal Dialysis Based on Matched Doses of Delivered Therapy. J. Am. Soc. Nephrol. 13: S48-52 [Abstract] [Full Text]  
• Copley, J. B. (2001). Resistance Training Enhances the Value of Protein Restriction in the Treatment of Chronic Kidney Disease. ANN INTERN MED 135: 999-1001 [Full Text]  
• Sarnak, M. J., Jaber, B. L. (2001). Pulmonary Infectious Mortality Among Patients With End-Stage Renal Disease. Chest 120: 1883-1887 [Abstract] [Full Text]  
• Peri, U. N., Fenves, A. Z., Middleton, J. P. (2001). Improving survival of octogenarian patients selected for haemodialysis. Nephrol Dial Transplant 16: 2201-2206 [Abstract] [Full Text]  
• GANESH, S. K., STACK, A. G., LEVIN, N. W., HULBERT-SHEARON, T., PORT, F. K. (2001). Association of Elevated Serum PO4, Ca PO4 Product, and Parathyroid Hormone with Cardiac Mortality Risk in Chronic Hemodialysis Patients. J. Am. Soc. Nephrol. 12: 2131-2138 [Abstract] [Full Text]  
• Schiffl, H., Lang, S. M., Stratakis, D., Fischer, R. (2001). Effects of ultrapure dialysis fluid on nutritional status and inflammatory parameters. Nephrol Dial Transplant 16: 1863-1869 [Abstract] [Full Text]  
• Clase, C. M., St Pierre, M. W., Churchill, D. N. (2001). Conversion between bromcresol green- and bromcresol purple-measured albumin in renal disease. Nephrol Dial Transplant 16: 1925-1929 [Abstract] [Full Text]  
• GIORDANO, M., FEO, P. D., LUCIDI, P., dePASCALE, E., GIORDANO, G., INFANTONE, L., ZOCCOLO, A. M., CASTELLINO, P. (2001). Increased Albumin and Fibrinogen Synthesis in Hemodialysis Patients with Normal Nutritional Status. J. Am. Soc. Nephrol. 12: 349-354 [Abstract] [Full Text]  
• Movilli, E., Carlo Cancarini, G., Zani, R., Camerini, C., Sandrini, M., Maiorca, R. (2001). Adequacy of dialysis reduces the doses of recombinant erythropoietin independently from the use of biocompatible membranes in haemodialysis patients. Nephrol Dial Transplant 16: 111-114 [Abstract] [Full Text]  
• Carfray, A., Patel, K., Whitaker, P., Garrick, P., Griffiths, G. J., Warwick, G. L. (2000). Albumin as an outcome measure in haemodialysis in patients: the effect of variation in assay method. Nephrol Dial Transplant 15: 1819-1822 [Abstract] [Full Text]  
• Kotler, D. P. (2000). Cachexia. ANN INTERN MED 133: 622-634 [Abstract] [Full Text]  
• Zenios, S. A., Fuloria, P. C. (2000). Managing the Delivery of Dialysis Therapy: A Multiclass Fluid Model Analysis. Management Science 46: 1317-1336 [Abstract]  
• Kairaitis, L. K., Yuill, E., Harris, D. C. H. (2000). Determinants of haemoglobin carbamylation in haemodialysis and peritoneal dialysis patients. Nephrol Dial Transplant 15: 1431-1437 [Abstract] [Full Text]