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Previous Volume 329:1123-1124 October 7, 1993 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Erice et al. (April 22 issue)¹ described a patient with symptomatic human immunodeficiency virus type 1 (HIV-1) infection who had a primary infection with a virus resistant to zidovudine. We report the case of a homosexual man in whom clinical symptoms of acute HIV-1 infection developed in May 1992; tests for HIV-1 antibodies were positive in July 1992. His most recent negative HIV-1 test was in November 1991.

We studied the presence of genotypic mutations at codons 215 and 74 of the HIV pol gene -- those associated with reduced sensitivity to zidovudine and didanosine, respectively. We . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Garcia-Lerma, J. G., MacInnes, H., Bennett, D., Weinstock, H., Heneine, W. (2004). Transmitted Human Immunodeficiency Virus Type 1 Carrying the D67N or K219Q/E Mutation Evolves Rapidly to Zidovudine Resistance In Vitro and Shows a High Replicative Fitness in the Presence of Zidovudine. J. Virol. 78: 7545-7552 [Abstract] [Full Text]