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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 329:1182-1190 October 14, 1993 Number 16
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Case 41-1993— A 66-Year-Old Woman with a 19-Year History of Progressive Weakness of All Extremities
Stasha C. Gominak, and Didier Cros

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Presentation of Case

A 66-year-old woman was referred to the hospital because of progressive weakness of all extremities.

The patient had been well until 19 years earlier, when she experienced the onset of a progressive left footdrop without pain, numbness, or paresthesias. A physician diagnosed intervertebral-disk disease, but no operation was advised. Twelve years before entry the patient began to have pains in the knees and hips, with muscular stiffness, and used analgesic medications almost daily. Five years before admission a marked waddle developed, and she began to walk with a cane; weakness developed in the arms. During the three years before entry . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnosis

Dr. Stasha C. Gominak's Diagnosis

Pathological Discussion

Anatomical Diagnoses

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