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Original Article
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Volume 329:1314-1316 October 28, 1993 Number 18
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Non-Corticosteroid-Associated Osteonecrosis of the Femoral Heads in Two Patients with Inflammatory Bowel Disease
Hugh J. Freeman, and W.C. Peter Kwan

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Osteonecrosis, or nontraumatic (aseptic, avascular) bone necrosis, is a relatively common disorder estimated to account for more than 10 percent of all joint replacements1. Although a number of clinical entities have been associated with osteonecrosis (e.g., Gaucher's disease, systemic lupus erythematosus, rheumatoid arthritis, hemoglobinopathies, air embolism, pancreatitis, and chronic alcoholism), the incidence and pathogenesis of osteonecrosis in each condition are not well defined. Some patients with osteonecrosis have also been treated with corticosteroids. It is not clear, however, if osteonecrosis in patients treated with corticosteroids represents a drug complication, a complication of the disease process, or both1,2,3,4,5.

Osteonecrosis . . . [Full Text of this Article]

Case Reports

Patient 1

Patient 2

Discussion


Source Information

From the Department of Medicine (Gastroenterology), University Hospital and University of British Columbia, Vancouver.

Address reprint requests to Dr. Freeman at ACU F-137, University Hospital (UBC Site), 2211 Wesbrook Mall, Vancouver, BC V6T 1W5, Canada.

References


Related Letters:

Osteonecrosis of the Femoral Heads in Inflammatory Bowel Disease
Stiles R. G., Carpenter W. A., Tigges S., Goffin E., Devuyst O., Freeman H. J.
Extract | Full Text  
N Engl J Med 1994; 330:791-792, Mar 17, 1994. Correspondence

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