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A correction has been published: N Engl J Med 1993;329(25):1904.

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Volume 329:1424-1426 November 4, 1993 Number 19
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Vitamin E and the Risk of Coronary Disease

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 by Steinberg, D.
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 by Rimm, E. B.
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To the Editor: The two studies suggesting a substantial reduction in the risk of coronary heart disease associated with the use of vitamin E supplements (May 20 issue)1,2 provide further compelling evidence about the importance of oxidation in the process of atherogenesis. We take issue, however, with the conclusion that it is premature to recommend vitamin E supplementation for the prevention of coronary heart disease3.

Until recently, physicians have generally maintained a healthy skepticism about vitamin supplementation, viewing it as unnecessary but probably harmless (when given in reasonable dose ranges). Vitamin E appears to provide substantial protection against coronary . . . [Full Text of this Article]

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