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Previous Volume 329:1432-1433 November 4, 1993 Number 19 Next

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Edited by Joshua Lederberg, Robert E. Shope, and Stanley C. Oaks, Jr. 294 pp. Washington, D.C., National Academy Press, 1992. $34.95. ISBN 0-309-04741-2.

Three decades ago this book would have been marketed as science fiction. Smallpox was on the verge of extinction, and health officials targeted measles, malaria, and other diseases for eradication. Powerful vaccines and drugs were poised to defeat microbial foes, one after another., and then the world seemed to change. Infectious diseases appeared and recrudesced in seemingly unpredictable, capricious ways.

In early 1991 the Institute of Medicine convened a distinguished committee to study emerging microbial threats, with a focus on threats to public health in the United States. The main premise of the study was that "anticipation and prevention of . . . [Full Text of this Article]

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