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Previous Volume 329:138-139 July 8, 1993 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Studies of the metastatic behavior of cancer suggest that one of the factors influencing the site at which tumor cells lodge is the presence of a special "soil" that favors the survival and growth of these tumor cells. A variety of hormonal and growth factors have been shown to influence the expansion of a metastatic colony.

One such factor is evidence that tumor cells and platelets interact to promote metastasis¹. Tumor cells can activate platelets that undergo the release reaction and make available as yet unidentified mediators that promote tumor growth. In some models, the degree . . . [Full Text of this Article]

References

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• Giese, A., Hagel, C., Kim, E. L., Zapf, S., Djawaheri, J., Berens, M. E., Westphal, M. (1999). Thromboxane synthase regulates the migratory phenotype of human glioma cells. Neuro Oncol Duke 1: 3-13 [Abstract]