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Correspondence
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Volume 329:141-142 July 8, 1993 Number 2
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Long-Term Treatment of Trichotillomania (Hair Pulling)

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To the Editor: In 1989 we reported that clomipramine was superior to desipramine in reducing hair-pulling symptoms in trichotillomania1. Three of the 13 subjects completing the initial double-blind crossover trial had complete remissions during the five weeks of clomipramine treatment, and 9 had at least a 50 percent reduction in the severity of symptoms. These benefits were maintained for six months. The chronicity of the disorder and reports of relapses after prolonged drug treatment1,2,3 raised the question of long-term outcome.

Follow-up information was obtained, by in-person interviews at 2 to 3 years and telephone updates at 4.3 ±0.6 years . . . [Full Text of this Article]

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