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Editorial
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Volume 329:1493-1494 November 11, 1993 Number 20
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Infants with Fever

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Fever in infants in the first three months of life is not infrequent. Although fever is usually self-limited, serious infections may be present, the most important of which are bacteremia and bacterial meningitis. Defining fever in infants is a complex issue, but most would agree that any rectal temperature of 38 °C or higher constitutes a fever.

At birth, the capacity of the immune system to defend against infectious pathogens is not fully developed. The capacity increases during the early months and years of life,1 with this evolution most pronounced during the first two to three months. The transition to . . . [Full Text of this Article]

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Related Letters:

Outpatient Management of Fever in Selected Infants
Baraff L. J., Madeley C.R., Peiris J.S.M., Craft A.W., Perry R. F., Garlisi A. P., Baker M. D., Bell L. M., Avner J.
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N Engl J Med 1994; 330:938-940, Mar 31, 1994. Correspondence

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