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Correspondence
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Volume 329:1503 November 11, 1993 Number 20
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Tretinoin for Hyperpigmentation in Black Patients

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 by Bulengo-Ransby, S. M.
To the Editor: In their report (May 20 issue), Bulengo-Ransby et al. concluded that topical tretinoin therapy lightened postinflammatory hyperpigmentation; it also lightened normal skin in black persons to a minimal degree.1 The authors have demonstrated only that tretinoin is useful in the treatment of acne, nothing more. Acne was the actual diagnosis in 62 of the 68 patients in the study. In many patients, acne lesions cause postinflammatory hyperpigmentation. Any control or diminution of the underlying disease will result in less hyperpigmentation. Over time (40 weeks in this study), preexisting areas of postinflammatory hyperpigmentation resolve or fade.

Since hyperpigmentation . . . [Full Text of this Article]

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