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Previous Volume 329:1514 November 11, 1993 Number 20

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Edited by Ronald W. Ellis. 418 pp., illustrated. New York, Marcel Dekker, 1993. $155. ISBN 0-8247-8780-3.

What an unfortunate title for an excellent monograph. This multiauthored book provides broad coverage of all aspects of the study of vaccines against hepatitis B virus (HBV). Only 4 of the 20 chapters relate to the use of these vaccines in clinical practice.

The chapters range from reviews of the biochemistry of HBV proteins and a detailed discussion of T- and B-cell epitopes of the PreS and surface-antigen regions, to descriptions of available HBV vaccines and those under development, the design and results of clinical trials, the epidemiology of HBV infection, HBV variants, strategies for global control of HBV infections, . . . [Full Text of this Article]

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