Epithelial cancer of the ovary is the fifth most common malignantcondition among women in the United States, with an annual incidenceof 22,000 new cases1. This disease predominantly affects postmenopausalwomen in their sixth decade, accounting for approximately 13,300deaths each year and for over half of all deaths from genitalcancer. The highly lethal nature of this tumor is related tothe absence of symptoms in the majority of women with earlystages of the disease. Seventy percent of women present withadvanced disease in which the tumor has spread to the peritonealsurfaces of the upper . . . [Full Text of this Article]
Risk Factors for Ovarian Cancer
Clinical Presentation
Staging and Surgical Treatment
Postoperative Treatment
Limited Disease (Stages I and II)
Advanced Disease (Stages III and IV)
Methods to Obtain a Complete Pathological Response in Advanced Ovarian Cancer
Treatment Options for Persistent or Recurrent Disease
Secondary Debulking Surgery
Intraperitoneal Chemotherapy
Radiotherapy
Systemic, Non-Cross-Resistant Chemotherapy
Autologous Bone Marrow Transplantation
Summary and Future Directions
Source Information
From the Division of Medical Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston.
Address reprint requests to Dr. Cannistra at the Dana-Farber Cancer Institute, 44 Binney St., Boston, MA 02115.
References
Related Letters:
Cancer of the Ovary
Lurain J., McKay M. J., Bull C. A., Collazos J., Embil J. M., Cannistra S. A.
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N Engl J Med 1994;
330:1012-1014, Apr 7, 1994.
Correspondence
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