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Correspondence
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Volume 329:1657-1658 November 25, 1993 Number 22
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Reversible Lymphomas

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 by Kamel, O. W.
To the Editor: Kamel et al. (May 6 issue)1 reported two cases of reversible lymphomas associated with methotrexate therapy for rheumatic diseases. As they noted, several years ago we made a similar observation2. Unlike their cases, the lymphoma we described originated in T lymphocytes. Although we did not report viral data at that time, we have examined specimens from this patient for viral genomic material using the polymerase chain reaction. We found that the samples contained copies of the cytomegalovirus genome but not of the Epstein-Barr virus or human herpesvirus 6 genome3.

We have subsequently seen a second . . . [Full Text of this Article]

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