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Previous Volume 329:1885-1887 December 16, 1993 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The health problems associated with hepatitis B virus (HBV) infection are immense. Roughly 5 percent of the world's population is chronically infected with HBV, and this is often said to be the chief cause of cirrhosis and hepatocellular carcinoma. Even in the United States, an area of low endemicity, there are more than 1 million carriers of the hepatitis B surface antigen (HBsAg). Cirrhosis develops in about 25 percent of carriers, and once it becomes clinically apparent, the chance of surviving five years is approximately 50 percent^1,2. The Centers for Disease Control and Prevention estimate that 4000 to 5000 . . . [Full Text of this Article]

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