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Correspondence
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Volume 329:1898 December 16, 1993 Number 25
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Autoimmune Protein S Deficiency

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 by D'Angelo, A.
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To the Editor: We were interested in the report by D'Angelo et al. of autoimmune protein S deficiency in a boy with severe thromboembolic disease (June 17 issue)1 and believe that the transient presence of anticardiolipin antibodies warrants more comment.

Recently, we described a 30-year-old man with deep-vein thrombosis and anticardiolipin antibodies in whom protein S activity was decreased and protein S antigen levels were normal2. Three months later, the patient had no detectable anticardiolipin antibodies and protein S activity and antigen were normal. Two other cases of anticardiolipin antibodies in association with acquired protein S deficiency have been . . . [Full Text of this Article]

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