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Previous Volume 329:1963 December 23, 1993 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Bunin et al. (Aug. 19 issue),¹ in their article on the relation between maternal diet and subsequent primitive neuroectodermal brain tumors, noted that in multivariant analyses, folate, early vitamin use, and iron supplements remained protective. In the mid-1980s in the United Kingdom, the use of multivitamin preparations containing folate and iron became common after work by Smithells et al. suggested that the use of such supplements prevented neural-tube defects². We examined the changing incidence of medulloblastoma, which made up over 90 percent of the primitive neuroectodermal tumors in the study by Bunin et al., in a . . . [Full Text of this Article]

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