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Book Review
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Volume 329:1973 December 23, 1993 Number 26
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The Molecular Foundations of Psychiatry

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By Steven E. Hyman and Eric J. Nestler. 239 pp., illustrated. Washington, D.C., American Psychiatric Press, 1993. $35. ISBN 0-88048-353-9.

This brief but important book fills a gap between clinical psychiatry and the rapidly evolving field of molecular neuroscience. Conceived neither as a textbook nor as a monograph, it is an overview of the molecular mechanisms of synaptic transmission, neuropsychopharmacology, neuroplasticity, and psychotropic drug actions. There is a lucid discussion of the pitfalls and promise of psychiatric genetics, along with a review of such techniques as linkage analysis and molecular cloning.

Because of the lag time inevitable in the publication process, there is no mention of the more recent advances in the field such as nitric oxide and carbon monoxide . . . [Full Text of this Article]




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