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Images in Clinical Medicine
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Volume 329:2001 December 30, 1993 Number 27
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Mycosis Fungoides

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Figure 1. Mycosis Fungoides.

Mycosis fungoides is an epidermotropic variant of cutaneous T-cell lymphoma. The most notable histologic features in the plaque stage include a broad, band-like, cellular lymphoid infiltrate involving the densely fibrotic superficial dermis (arrows, Panel A). The lymphoid cells are small to medium in size and contain hyperconvoluted nuclei. The epidermis is involved when atypical lymphocytes form multiple nonspongiotic aggregates of Pautrier's microabscesses (arrows, Panel B). (Hematoxylin and eosin; Panel A, x60; Panel B, x240.).

 


Tai-Yuen Wong, M.D.
Martin C. Mihm, Jr., M.D.
Massachusetts General Hospital
Boston, MA 02114


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