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Previous Volume 329:203-204 July 15, 1993 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Human herpesvirus 6 (HHV-6) was discovered in 1986 by Salahuddin and coworkers¹ and was initially called human B-lymphotropic virus. The virus was later shown to have a marked tropism for CD4-positive T cells and was renamed HHV-6. HHV-6 is genetically similar to cytomegalovirus,² and the two viruses share phenotypic properties such as patterns of in vitro sensitivity to antiviral drugs³. This novel herpesvirus was quickly singled out as a potential human pathogen. In 1988, Yamanishi and coworkers⁴ showed that HHV-6 was the cause of exanthem subitum (roseola infantum, or sixth disease). They isolated the virus from peripheral-blood mononuclear cells . . . [Full Text of this Article]

References

Related Letters:

Primary Human Herpesvirus 6 Infection in an Adult
Morris D. J., Appleton A. L., Sviland L., Schmidt C.A., Wilborn F.F., Siegert W., Cone R., Corey L., Hackman R., Akashi K., Eizuru Y., Sumiyoshi Y.
Extract | Full Text  
N Engl J Med 1993; 329:1817-1819, Dec 9, 1993. Correspondence

This article has been cited by other articles:

• Lacoste, V., Verschoor, E. J., Nerrienet, E., Gessain, A. (2005). A novel homologue of Human herpesvirus 6 in chimpanzees. J. Gen. Virol. 86: 2135-2140 [Abstract] [Full Text]  
• Morris, D. J., Appleton, A. L., Sviland, L., Schmidt, C.A., Wilborn, F.F., Siegert, W., Cone, R., Corey, L., Hackman, R., Akashi, K., Eizuru, Y., Sumiyoshi, Y. (1993). Primary Human Herpesvirus 6 Infection in an Adult. NEJM 329: 1817-1819 [Full Text]