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Volume 329:279 July 22, 1993 Number 4
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Clinical Problem-Solving: Lucky Lady

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 by Ben-Chetrit, E.
To the Editor: With reference to the Clinical Problem-Solving case in the March 4 issue,1 I was surprised that autoimmune hemolytic anemia and neutropenia were not considered in the differential diagnosis.

A pregnant woman taking 5 mg of oral prednisone daily for stable systemic lupus erythematosus presented with severe pitting edema of both legs, a grade 2 systolic murmur, and a hemoglobin level of 6.8 g per deciliter. She was treated for kidney involvement with 300 mg of intravenous hydrocortisone a day and with azathioprine, but three weeks later pneumocystis pneumonia developed. She was treated with trimethoprim-sulfamethoxazole, and agranulocytosis developed. . . . [Full Text of this Article]

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