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Previous Volume 329:360-361 July 29, 1993 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Dr. Mazzaferri (Feb. 25 issue)¹ recommends the use of radionuclide scanning when fine-needle aspiration biopsy yields indeterminate results in the evaluation of a solitary thyroid nodule. This is done to identify hot nodules that can then be observed or treated medically. A hot nodule, by definition, autonomously secretes thyroxine in sufficient quantity to suppress thyroid-stimulating hormone (TSH), with the result that the presumably normal extranodular thyroid tissue shows no uptake on scintigraphic scanning². Thus, a hot nodule shows uptake only in the region of the nodule.

A more cost-effective method of screening would be to use . . . [Full Text of this Article]

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