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Previous Volume 329:500-501 August 12, 1993 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The recognition of associations between HLA antigens and a variety of diseases has stimulated many immunologic studies of the pathogenesis of complex human diseases. This is particularly true of autoimmune diseases^1,2 and, more recently, some reproductive disorders^3,4. In interpreting these associations, however, one must avoid the pitfall of looking for a lost key under the nearest street lamp, not because that is where it was lost but because that is where the light is.

There remains much to learn about the structure and function of the 3800-to-4000-kilobase segment of the human genome that encompasses the major histocompatibility complex (MHC) . . . [Full Text of this Article]

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