FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 329:665-666 August 26, 1993 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

To the Editor: The Food and Drug Administration, after receiving 6 reports of benign intracranial hypertension (pseudotumor cerebri) in patients treated with recombinant growth hormone, actively identified an additional 17 affected patients in the United States or abroad. Benign intracranial hypertension was also reported in three patients with resistance to growth hormone who were treated with insulin-like growth factor I, the primary mediator of the actions of growth hormone.

The 23 cases -- 22 in children and 1 in an adult -- associated with growth hormone treatment occurred between 1986 and 1993. Among the children, seven had growth hormone deficiency, . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Chernausek, S. D., Backeljauw, P. F., Frane, J., Kuntze, J., Underwood, L. E., for the GH Insensitivity Syndrome Collaborative Gr, (2007). Long-Term Treatment with Recombinant Insulin-Like Growth Factor (IGF)-I in Children with Severe IGF-I Deficiency due to Growth Hormone Insensitivity. J. Clin. Endocrinol. Metab. 92: 902-910 [Abstract] [Full Text]  
• Molitch, M. E., Clemmons, D. R., Malozowski, S., Merriam, G. R., Shalet, S. M., Vance, M. L., for The Endocrine Society's Clinical Guidelines Su, (2006). Evaluation and Treatment of Adult Growth Hormone Deficiency: An Endocrine Society Clinical Practice Guideline. J. Clin. Endocrinol. Metab. 91: 1621-1634 [Abstract] [Full Text]  
• Harman, S. M., Blackman, M. R. (2004). Hormones and Supplements: Do They Work?: Use of Growth Hormone for Prevention or Treatment of Effects of Aging. J. Gerontol. A Biol. Sci. Med. Sci. 59: B652-B658 [Abstract] [Full Text]  
• Blackman, M. R., Sorkin, J. D., Munzer, T., Bellantoni, M. F., Busby-Whitehead, J., Stevens, T. E., Jayme, J., O'Connor, K. G., Christmas, C., Tobin, J. D., Stewart, K. J., Cottrell, E., St. Clair, C., Pabst, K. M., Harman, S. M. (2002). Growth Hormone and Sex Steroid Administration in Healthy Aged Women and Men: A Randomized Controlled Trial. JAMA 288: 2282-2292 [Abstract] [Full Text]  
• Katz, S. E., Klisovic, D. D., O'Dorisio, M. S., Lynch, R., Lubow, M. (2002). Expression of Somatostatin Receptors 1 and 2 in Human Choroid Plexus and Arachnoid Granulations: Implications for Idiopathic Intracranial Hypertension. Arch Ophthalmol 120: 1540-1543 [Abstract] [Full Text]  
• Bechtold, S., Butenandt, O., Meidert, A., Boergen, K.-P., Schmidt, H. (2001). Persistent Papilledema in Ulirich-Turner Syndrome Treated with Growth Hormone. CLIN PEDIATR 40: 629-631  
• ROELFSEMA, V., CLARK, R. G. (2001). The Growth Hormone and Insulin-Like Growth Factor Axis: Its Manipulation for the Benefit of Growth Disorders in Renal Failure. J. Am. Soc. Nephrol. 12: 1297-1306 [Abstract] [Full Text]  
• Carroll, P. V., Christ the members of Growth Hormone Research Soci, E. R., Bengtsson, B. A., Carlsson, L., Christiansen, J. S., Clemmons, D., Hintz, R., Ho, K., Laron, Z., Sizonenko, P., Sönksen, P. H., Tanaka, T., Thorner, M. (1998). Growth Hormone Deficiency in Adulthood and the Effects of Growth Hormone Replacement: A Review. J. Clin. Endocrinol. Metab. 83: 382-395 [Abstract] [Full Text]  
• Committee on Drugs and Committee on Bioethics, (1997). Considerations Related to the Use of Recombinant Human Growth Hormone in Children. Pediatrics 99: 122-129 [Abstract] [Full Text]