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In 1988, the Centers for Disease Control described chronic fatigue syndrome and proposed a research case definition for it. This move classified an interrelated but heterogeneous array of debilitating symptoms under a new name. There has now been sufficient opportunity to apply this case definition and to accumulate abundant clinical and research data and anecdotal experiences with which to formulate hypotheses regarding the pathogenesis of this entity. Two very different scholarly books have emerged from the large lay and professional literature reporting on that experience.
Jenkins, a psychiatrist, and Mowbray, an immunopathologist, have assembled an ambitious book consisting of 29
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