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Previous Volume 330:827-838 March 24, 1994 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Bone marrow transplantation is the intravenous infusion of hematopoietic progenitor cells to reestablish marrow function in a patient with damaged or defective bone marrow (Figure 1). Although some have traced the origin of this procedure to the end of the past century, when patients were given bone marrow orally as a treatment for hematologic disorders,¹ a more realistic starting point is a 1939 report of a patient who received 18 ml of intravenous marrow from his brother as a treatment for aplastic anemia². The beginning of modern bone marrow transplantation can be traced to work showing that . . . [Full Text of this Article]

Allogeneic and Syngeneic Bone Marrow Transplantation

Autologous Bone Marrow Transplantation

Methods of Transplantation

Complications

Graft-versus-Host Disease

Graft Rejection

Pulmonary Complications

Veno-occlusive Disease of the Liver

Diseases Treated by Bone Marrow Transplantation

Nonmalignant Diseases

            Aplastic Anemia

            Thalassemia and Sickle Cell Anemia

            Immunodeficiency Disorders

            Other Genetic Disorders

Malignant Diseases

            Acute Myeloid Leukemia

            Myelodysplastic Syndrome

            Acute Lymphoblastic Leukemia

            Chronic Myelogenous Leukemia

            Chronic Lymphocytic Leukemia

            Multiple Myeloma

            Non-Hodgkin's Lymphoma

            Hodgkin's Disease

            Neuroblastoma

            Breast Cancer

            Testicular Carcinoma

            Other Solid Tumors

The Future of Bone Marrow Transplantation

Source Information

From the Department of Internal Medicine, University of Nebraska Medical Center, 600 S. 42nd St., Omaha, NE 68198-3332, where reprint requests should be addressed to Dr. Armitage.

References

Related Letters:

Bone Marrow Transplantation
Elias A., Armitage J. O.
Extract | Full Text  
N Engl J Med 1994; 331:617, Sep 1, 1994. Correspondence

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