FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 330:865-867 March 24, 1994 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by The Cystic Fibrosis Genotype-Phenotype Consortium PubMed Citation

To the Editor: In a recent article Hamosh and Corey of the Cystic Fibrosis Genotype-Phenotype Consortium (Oct. 28 issue)¹ reported on correlations between the genotypes and phenotypes of patients with cystic fibrosis. The mean age of the patients with the R117H/F₅₀₈ genotype was 23.5 years, and the ages of the other groups ranged from 11.0 to 14.6 years. The authors conclude that genotype is predictive of pancreatic status but not of the severity of pulmonary disease.

In our adult patient population, however, we found a correlation between the genotype and the severity of pulmonary disease. The rate of decline . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Dugueperoux, I., De Braekeleer, M. (2005). The CFTR 3849+10kbC->T and 2789+5G->A alleles are associated with a mild CF phenotype. Eur Respir J 25: 468-473 [Abstract] [Full Text]  
• Gan, K.-H., Veeze, H. J., van den Ouweland, A., Halley, D., Scheffer, H., van der Hout, A., Overbeek, S. E., de Jongste, J. C., Bakker, W., Heijerman, H. (1995). A Cystic Fibrosis Mutation Associated with Mild Lung Disease. NEJM 333: 95-99 [Abstract] [Full Text]