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Editorial
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Volume 330:932-934 March 31, 1994 Number 13
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Herpes Zoster with Postherpetic Neuralgia -- Persisting Pain and Frustration

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Herpes zoster (shingles) is an acute infection of the dorsal-root ganglia and skin caused by a reactivation of varicella-zoster virus, the cause of chickenpox. It is characterized by pain and vesicles on an erythematous base limited to one to three dermatomes. In immunocompromised persons, widespread viral infection of skin (disseminated zoster) and viscera may lead to fatal pneumonitis, hepatitis, or encephalitis.

Zoster is common. The annual incidence in the United States is 4 per 1000 population1. After the age of 50 years, the rate of zoster increases to 5.1 per 1000 patients, and among octogenarians it is 10.1 per . . . [Full Text of this Article]

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