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Previous Volume 330:1129-1135 April 21, 1994 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The heart shares with other organs a susceptibility to immune-mediated injury. However, the unique clinical expressions of myocardial inflammation have only recently received investigative scrutiny. It is now clear that numerous cardiac diseases characterized by the presence of inflammatory cells within the myocardium result from immune sensitization to endogenous or exogenous cardiac antigens. The consequent reaction of cardiac myocytes to immune injury can range from reversible modulation of their electrical and mechanical capabilities to cell death.

Immune Pathways of Injury

Effector mechanisms of immune-mediated injury are traditionally divided into humoral and cellular types. Humoral immunity requires recognition of an epitope by antibody for specificity . . . [Full Text of this Article]

Cardiac Diseases Associated with Myocarditis

Immune Effector Mechanisms in Cardiac-Allograft Rejection

Immune Effector Mechanisms in Viral Myocarditis

Immune Modulation of Cardiac Function

Treatment of Lymphocytic Cardiomyopathies

Summary

Source Information

From CV Therapeutics, 1615 Plymouth St., Mountain View, CA 94043, where reprint requests should be addressed to Dr. Lange.

References

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