From mild disease to multiorgan failure and sepsis, acute pancreatitisis a disorder that has numerous causes, an obscure pathogenesis,few effective remedies, and an often unpredictable outcome.In 1925, Moynihan aptly described the dramatic nature of acutepancreatitis as the "most terrible of all calamities that occurin connection with the abdominal viscera. The suddenness ofits onset, the illimitable agony which accompanies it, and themortality attendant upon it render it the most formidable ofcatastrophes"1. Just over 100 years ago, Reginald Fitz2 describedmany of the modern clinical and pathologic features of severeacute pancreatitis3. . . . [Full Text of this Article]
Epidemiology
Causes of Acute Pancreatitis
Obstructive Causes
Toxins and Drugs
Trauma
Metabolic Causes
Infection
Miscellaneous Causes
Idiopathic Pancreatitis
Acute Pancreatitis in Children
Pathophysiology
Diagnosis
Prognostic Indicators
Natural History and Complications
Treatment
Source Information
From the Departments of Medicine (W.S.) and Health Care Sciences (S.T.), Division of Gastroenterology, George Washington University Medical Center, Washington, D.C.
Address reprint requests to Dr. Steinberg at the Division of Gastroenterology, George Washington University Medical Center, 2150 Pennsylvania Ave., NW, Washington, DC 20037.
References
Related Letters:
Acute Pancreatitis
Lerch M. M., Hernandez C. A., Adler G., Colombo J. L., Jensen G. L., Blackburn G. L., Castiella A., Cosme A., Arenas J. I.
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N Engl J Med 1994;
331:948-949, Oct 6, 1994.
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