FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 330:1310-1311 May 5, 1994 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

In 1983, Warren and Marshall discovered a spiral urease-producing organism in the human stomach, later classified as Helicobacter pylori¹. H. pylori has been shown to be strongly associated with peptic ulcer disease, and antibiotic therapy to eradicate this organism is an important treatment for duodenal and gastric ulcers². In many countries, the prevalence of H. pylori infection in adults is 35 percent or more, although most infected people have no symptoms.

H. pylori has also been associated with gastric carcinoma. Correa described four steps already taken to establish the association³. The first was to observe that H. . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Matsumoto, M., Hara, K., Kimata, H., Benno, Y., Shimamoto, C. (2005). Exfoliation of Helicobacter pylori from Gastric Mucin by Glycopolypeptides from Buttermilk. J DAIRY SCI 88: 49-54 [Abstract] [Full Text]  
• Bahler, D. W., Swerdlow, S. H. (1998). Clonal Salivary Gland Infiltrates Associated With Myoepithelial Sialadenitis (Sjogren's Syndrome) Begin as Nonmalignant Antigen-Selected Expansions. Blood 91: 1864-1872 [Abstract] [Full Text]  
• Molinari, M., Galli, C., Norais, N., Telford, J. L., Rappuoli, R., Luzio, J. P., Montecucco, C. (1997). Vacuoles Induced by Helicobacter pylori Toxin Contain Both Late Endosomal and Lysosomal Markers. J. Biol. Chem. 272: 25339-25344 [Abstract] [Full Text]  
• Sorrentino, D., Ferraccioli, G.F., DeVita, S., Labombarda, A., Boiocchi, M., Bartoli, E. (1997). Hepatitis C Virus Infection and Gastric Lymphoproliferation in Patients With Sjogren's Syndrome. Blood 90: 2116-2117 [Full Text]  
• Walsh, J. H., Peterson, W. L. (1995). The Treatment of Helicobacter pylori Infection in the Management of Peptic Ulcer Disease. NEJM 333: 984-991 [Full Text]