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Previous Volume 330:1314-1315 May 5, 1994 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Despite evidence of HIV in the saliva of HIV-positive persons, oral transmission of the virus appears to be a rare event. Researchers have isolated infectious virus from only a small percentage of saliva samples from HIV-infected patients, even when virus can be isolated from peripheral-blood samples from the same persons^1,2 or when HIV DNA is detected in saliva by the polymerase chain reaction³.

Components of saliva can inhibit HIV⁴ and other viruses⁵. Can the presence of salivary viral inhibitors explain the low rate of recovery of HIV from oral fluids? Recently, we tested saliva samples . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Ikuta, K., Suzuki, S., Horikoshi, H., Mukai, T., Luftig, R. B. (2000). Positive and Negative Aspects of the Human Immunodeficiency Virus Protease: Development of Inhibitors versus Its Role in AIDS Pathogenesis. Microbiol. Mol. Biol. Rev. 64: 725-745 [Abstract] [Full Text]  
• Baqui, A. A. M. A., Meiller, T. F., Falkler, W. A. Jr. (1999). Enhanced Secretory Leukocyte Protease Inhibitor in Human Immunodeficiency Virus Type 1-Infected Patients. CVI 6: 808-811 [Abstract] [Full Text]  
• Baron, S., Poast, J., Cloyd, M. W. (1999). Why Is HIV Rarely Transmitted by Oral Secretions?: Saliva Can Disrupt Orally Shed, Infected Leukocytes. Arch Intern Med 159: 303-310 [Abstract] [Full Text]  
• McNeely, T. B., Shugars, D. C., Rosendahl, M., Tucker, C., Eisenberg, S. P., Wahl, S. M. (1997). Inhibition of Human Immunodeficiency Virus Type 1 Infectivity by Secretory Leukocyte Protease Inhibitor Occurs Prior to Viral Reverse Transcription. Blood 90: 1141-1149 [Abstract] [Full Text]